ID A0A0A0AF55_CHAVO Unreviewed; 669 AA.
AC A0A0A0AF55;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=GMP synthase (glutamine-hydrolyzing) {ECO:0000256|ARBA:ARBA00012746};
DE EC=6.3.5.2 {ECO:0000256|ARBA:ARBA00012746};
DE AltName: Full=Glutamine amidotransferase {ECO:0000256|ARBA:ARBA00031356};
DE Flags: Fragment;
GN ORFNames=N301_00522 {ECO:0000313|EMBL:KGL92786.1};
OS Charadrius vociferus (Killdeer) (Aegialitis vocifera).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Charadriiformes; Charadriidae; Charadrius.
OX NCBI_TaxID=50402 {ECO:0000313|EMBL:KGL92786.1, ECO:0000313|Proteomes:UP000053858};
RN [1] {ECO:0000313|EMBL:KGL92786.1, ECO:0000313|Proteomes:UP000053858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N301 {ECO:0000313|EMBL:KGL92786.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln
CC route): step 1/1. {ECO:0000256|ARBA:ARBA00005153}.
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DR EMBL; KL871660; KGL92786.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A0AF55; -.
DR STRING; 50402.A0A0A0AF55; -.
DR UniPathway; UPA00189; UER00296.
DR Proteomes; UP000053858; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003921; F:GMP synthase activity; IEA:InterPro.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd01742; GATase1_GMP_Synthase; 1.
DR CDD; cd01997; GMP_synthase_C; 1.
DR Gene3D; 3.30.300.10; -; 2.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR017926; GATASE.
DR InterPro; IPR001674; GMP_synth_C.
DR InterPro; IPR004739; GMP_synth_GATase.
DR InterPro; IPR025777; GMPS_ATP_PPase_dom.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00888; guaA_Nterm; 1.
DR PANTHER; PTHR11922:SF2; GMP SYNTHASE [GLUTAMINE-HYDROLYZING]; 1.
DR PANTHER; PTHR11922; GMP SYNTHASE-RELATED; 1.
DR Pfam; PF00117; GATase; 1.
DR Pfam; PF00958; GMP_synt_C; 1.
DR PRINTS; PR00097; ANTSNTHASEII.
DR PRINTS; PR00096; GATASE.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR SUPFAM; SSF54810; GMP synthetase C-terminal dimerisation domain; 2.
DR PROSITE; PS51273; GATASE_TYPE_1; 1.
DR PROSITE; PS51553; GMPS_ATP_PPASE; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00886};
KW Glutamine amidotransferase {ECO:0000256|ARBA:ARBA00022962,
KW ECO:0000256|PROSITE-ProRule:PRU00605};
KW GMP biosynthesis {ECO:0000256|ARBA:ARBA00022749, ECO:0000256|PROSITE-
KW ProRule:PRU00886}; Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00886};
KW Purine biosynthesis {ECO:0000256|ARBA:ARBA00022755, ECO:0000256|PROSITE-
KW ProRule:PRU00886}; Reference proteome {ECO:0000313|Proteomes:UP000053858}.
FT DOMAIN 190..411
FT /note="GMPS ATP-PPase"
FT /evidence="ECO:0000259|PROSITE:PS51553"
FT ACT_SITE 97
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 183
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 185
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT BINDING 221..227
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00886"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KGL92786.1"
FT NON_TER 669
FT /evidence="ECO:0000313|EMBL:KGL92786.1"
SQ SEQUENCE 669 AA; 74191 MW; F617419457F38C76 CRC64;
SQPENAGGDL KDGQHHYEGA VVILDAGAQY GKVIDRRVRE LFVQSEIFPL ETPAFAIREQ
GFRAIIISGG PNSVYAEDAP WFDPAIFTIG KPVLGICYGM QMMNKVFGGT VHKKSVREDG
VFSITLDNTC SLFRGLQKEE LVLLTHGDSV DKVADGFKVV AQSGNIIAGI ANESKKLYGA
QFHPEVSLTV NGKMILKNFL YDIAGCSGTF TVENRELQCI QDIKEKVGSS KVLVTLNRDQ
VIAVHIDNGF MRKRESQSVE EALKKLGIQV KVVNAAHSFY NGTTTLPISD EDRTPRKRIS
KTLNMTTSPE EKRKIIGDTF VKIANEVIGE MNLKPEEVFL AQGTLRPDLI ESASLVASGK
AEVIKTHHND TELIRKLREE GKVIEPLKDF HKDEVRVLGR ELGLPEELVS RHPFPGPGLA
IRVICAEEPY VCKDFPETNN ILKIVADFSA SVKKPHTLLQ RVKACTTEED QEKLMQITSL
HSLNAFLLPI KTVGVQGDCR SYSYVCGISS KDAPHWESLM FLARLIPRMC HNINRVVYVF
GPPVKEPPTD VTPTFLTTGV LSTLRQADFE AHNILRESGY AGKISQMPII LTPLHFDRDP
LQKQPSCQRS VVIRTFITSD FMTGIAATPG NEVPEEVVLK MVAEIKKIPG ISRVMYDLTS
KPPGTTEWE
//
