ID A0A0A0K6L8_CUCSA Unreviewed; 1121 AA.
AC A0A0A0K6L8;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=PX domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=Csa_7G446900 {ECO:0000313|EMBL:KGN45375.1};
OS Cucumis sativus (Cucumber).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3659 {ECO:0000313|EMBL:KGN45375.1, ECO:0000313|Proteomes:UP000029981};
RN [1] {ECO:0000313|EMBL:KGN45375.1, ECO:0000313|Proteomes:UP000029981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 9930 {ECO:0000313|Proteomes:UP000029981};
RX PubMed=19881527; DOI=10.1038/ng.475;
RA Huang S., Li R., Zhang Z., Li L., Gu X., Fan W., Lucas W.J., Wang X.,
RA Xie B., Ni P., Ren Y., Zhu H., Li J., Lin K., Jin W., Fei Z., Li G.,
RA Staub J., Kilian A., van der Vossen E.A., Wu Y., Guo J., He J., Jia Z.,
RA Ren Y., Tian G., Lu Y., Ruan J., Qian W., Wang M., Huang Q., Li B.,
RA Xuan Z., Cao J., Asan null, Wu Z., Zhang J., Cai Q., Bai Y., Zhao B.,
RA Han Y., Li Y., Li X., Wang S., Shi Q., Liu S., Cho W.K., Kim J.Y., Xu Y.,
RA Heller-Uszynska K., Miao H., Cheng Z., Zhang S., Wu J., Yang Y., Kang H.,
RA Li M., Liang H., Ren X., Shi Z., Wen M., Jian M., Yang H., Zhang G.,
RA Yang Z., Chen R., Liu S., Li J., Ma L., Liu H., Zhou Y., Zhao J., Fang X.,
RA Li G., Fang L., Li Y., Liu D., Zheng H., Zhang Y., Qin N., Li Z., Yang G.,
RA Yang S., Bolund L., Kristiansen K., Zheng H., Li S., Zhang X., Yang H.,
RA Wang J., Sun R., Zhang B., Jiang S., Wang J., Du Y., Li S.;
RT "The genome of the cucumber, Cucumis sativus L.";
RL Nat. Genet. 41:1275-1281(2009).
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DR EMBL; CM002928; KGN45375.1; -; Genomic_DNA.
DR RefSeq; XP_011659569.1; XM_011661267.1.
DR AlphaFoldDB; A0A0A0K6L8; -.
DR STRING; 3659.A0A0A0K6L8; -.
DR EnsemblPlants; KGN45375; KGN45375; Csa_7G446900.
DR GeneID; 101219007; -.
DR Gramene; KGN45375; KGN45375; Csa_7G446900.
DR KEGG; csv:101219007; -.
DR eggNOG; KOG2101; Eukaryota.
DR OMA; PLENFDN; -.
DR OrthoDB; 2899602at2759; -.
DR Proteomes; UP000029981; Chromosome 7.
DR GO; GO:0005768; C:endosome; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22999:SF28; PHOX (PX) DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22999; PX SERINE/THREONINE KINASE PXK; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029981};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 104..287
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 673..786
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 362..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 571..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 847..903
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..384
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..599
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 876..890
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1121 AA; 127052 MW; 342B0E1C557A4DF4 CRC64;
MSSQNQVTPR DLLEEAKKRV LFLVICIVGL SYMMSLTSSS VWVNLPAAAF LIILIRYFSL
DLEMRRKAAS YIRRPLPEHG ISQEKPLEFP KVVKKSEWRR KVNSRVAEDA IDHFSRHLIS
EWVTDLWYSR LTPDKEGPEE LINIVNGVLG EIAGRFRNIN LIDLLMRDLI NLICTHLENF
RSTKLKIEKR QLGTITLEKL DTELRQHLAM ENRLHPALFS SEAQHKVLQH VMDGLILYTF
KHENLQCLYF RYTARELLAS AVMRPVLNLA SPRFINERIE SLVINMKKPK TVESMHENLG
SKTDGSPSIP SDDLSKFLDP SMAGVELVQM KNAQSTTPTN LPTKFNCNAS FSKDPLLSID
TRSSRSWNSE PPTSQNVHEN TVQKHNSGEW GEKLDQFSRR KDKALAPEHF ENMWAKGRNY
KMKENENQSN KNTQHGLPQG KPLSISVKRE KRISKTIDIE NEGELNCSKN KTVHLGCTDP
LTVNGSSCRT DSDILNNSTV MHYQDNDRDV MHLNDLDSDG NTSEDEETSN VTGLDSPVTK
VWNARNNRNA GISHIHHPLE SSDGCRVKKA VKGKDHNNRL SRNQSGRKRS RHNSEKLPVW
QEVERTSFIS GDGQDILNSP LGPANDDDSS DDSDMESSGR IHSGAAASSS VLSISHILPT
DYSQSSQMVD SFFRLKCEVM GANIVKSGSR TFAVYSISVT DVNNNHSWSI KRRFSHFEEL
HRRLKEFSEY NLHLPPKHFL STGLDFPVIQ ERCNLLDKYL KRLIQLPRIS GSIEVWDFLS
VDSQTYIFLD SFSIIETLSV DPADKSHEEY NRCVSNPNSP LSGLLPLRRD HATAEFFEPK
LQSKAKLQPN GLRLNSKDAT TEKSGLPDRN SGRTENQKEN GTLSDKNSGN TENQKENEKS
GEASDLLLDA ATDPMLPTEW VPPNLTVPIF NLVDVIFQLQ DGGWIRRKAF WVAKQVLQLG
MGDALEDWLI QKIQRFRKGS SMASAINRLE QILWPGGVFI TKRPKQPPSP EGSTSGNNSN
EILSPRSLEE LQQQEADRRA KLVYDLMITN APPAIVGLVG RKEYEQCAKD LYYFLQSAVC
TKLLALDLIE LLLLTLFPEL DSVFKQLHER KEKFGKLDAH V
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