ID A0A0A1DHH2_NOCSI Unreviewed; 463 AA.
AC A0A0A1DHH2;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 2.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=phospholipase D {ECO:0000256|ARBA:ARBA00012027};
DE EC=3.1.4.4 {ECO:0000256|ARBA:ARBA00012027};
GN ORFNames=KR76_08705 {ECO:0000313|EMBL:AIY16826.2};
OS Nocardioides simplex (Arthrobacter simplex).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Pimelobacter.
OX NCBI_TaxID=2045 {ECO:0000313|EMBL:AIY16826.2, ECO:0000313|Proteomes:UP000030300};
RN [1] {ECO:0000313|EMBL:AIY16826.2, ECO:0000313|Proteomes:UP000030300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM Ac-2033D {ECO:0000313|EMBL:AIY16826.2,
RC ECO:0000313|Proteomes:UP000030300};
RX PubMed=25573942;
RA Shtratnikova V.Y., Schelkunov M.I., Pekov Y.A., Fokina V.V.,
RA Logacheva M.D., Sokolov S.L., Bragin E.Y., Ashapkin V.V., Donova M.V.;
RT "Complete Genome Sequence of Steroid-Transforming Nocardioides simplex VKM
RT Ac-2033D.";
RL Genome Announc. 3:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC sn-glycero-3-phosphate + choline + H(+); Xref=Rhea:RHEA:14445,
CC ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58608; EC=3.1.4.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000798};
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DR EMBL; CP009896; AIY16826.2; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A1DHH2; -.
DR STRING; 2045.KR76_08705; -.
DR KEGG; psim:KR76_08705; -.
DR eggNOG; COG1502; Bacteria.
DR HOGENOM; CLU_047394_0_0_11; -.
DR Proteomes; UP000030300; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR025202; PLD-like_dom.
DR PANTHER; PTHR43856; CARDIOLIPIN HYDROLASE; 1.
DR PANTHER; PTHR43856:SF1; MITOCHONDRIAL CARDIOLIPIN HYDROLASE; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030300}.
FT DOMAIN 91..236
FT /note="Phospholipase D-like"
FT /evidence="ECO:0000259|Pfam:PF13091"
FT REGION 49..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..67
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 463 AA; 51069 MW; AD19883F5CAC26A6 CRC64;
MMRRAGTGFV IGVTALAVGL GLGALPGAHA SAPEPTVAVV APSSVEASAP AAVDRKKKAK
RDHYNPNPGL RFNEPYSRGG KKATNIRRHI LRSIDSTRKG DVIQMAAWNI RGRSWMNALI
RAHKRGVAVQ VIMDKVNWSR EHPNPEAAAV AKVLKGKENR PVQSWLRTCA GSCRGARGIP
HSKFYLFSRV EDRKYVTMFG SNNATDVAAN DQWNDLYTWV NNKTIYDTFV NVFNQMKLDK
NQGSKGYVAA KFSPTQSVFF YPYKGAVPTK VGDPDMARLN QIKCTGATGG AGYNGRTKIR
IMQTAIHGDR GIRLAQKLVQ LKKAGCDIRI VYALMGNNVH QLLTANKVQK LQLAYDRDRN
GVYDIYLHLK SLAISGNYQG VTNARVTYNG SANWSSVPLA SDDVVGEFRD VAMTKAYIDW
TDFLYNHRPG SWGSVNLAPV KSSVVEGRIM PVDPYSFMKE NGL
//
