ID   A0A0A1SZS5_9HYPO        Unreviewed;       648 AA.
AC   A0A0A1SZS5;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CEJ90336.1};
GN   ORFNames=VHEMI06127 {ECO:0000313|EMBL:CEJ90336.1};
OS   [Torrubiella] hemipterigena.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae;
OC   Clavicipitaceae incertae sedis; 'Torrubiella' clade.
OX   NCBI_TaxID=1531966 {ECO:0000313|EMBL:CEJ90336.1, ECO:0000313|Proteomes:UP000039046};
RN   [1] {ECO:0000313|EMBL:CEJ90336.1, ECO:0000313|Proteomes:UP000039046}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Horn F., Habel A., Scharf D.H., Dworschak J., Brakhage A.A., Guthke R.,
RA   Hertweck C., Linde J.;
RT   "Draft Genome Sequence and Gene Annotation of the Entomopathogenic Fungus
RT   Verticillium hemipterigenum.";
RL   Genome Announc. 3:e01439-e01414(2015).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC   -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|ARBA:ARBA00007441}.
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DR   EMBL; CDHN01000003; CEJ90336.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0A1SZS5; -.
DR   STRING; 1531966.A0A0A1SZS5; -.
DR   HOGENOM; CLU_422838_0_0_1; -.
DR   OrthoDB; 2255863at2759; -.
DR   Proteomes; UP000039046; Unassembled WGS sequence.
DR   GO; GO:0004069; F:L-aspartate:2-oxoglutarate aminotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00609; AAT_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR005000; Aldolase/citrate-lyase_domain.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR000796; Asp_trans.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR   PANTHER; PTHR11879; ASPARTATE AMINOTRANSFERASE; 1.
DR   PANTHER; PTHR11879:SF20; ASPARTATE AMINOTRANSFERASE; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   Pfam; PF03328; HpcH_HpaI; 1.
DR   PRINTS; PR00799; TRANSAMINASE.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000039046}.
FT   DOMAIN          29..399
FT                   /note="Aminotransferase class I/classII"
FT                   /evidence="ECO:0000259|Pfam:PF00155"
FT   DOMAIN          408..595
FT                   /note="HpcH/HpaI aldolase/citrate lyase"
FT                   /evidence="ECO:0000259|Pfam:PF03328"
SQ   SEQUENCE   648 AA;  70640 MW;  02D9B7388382FB00 CRC64;
     MSLFDQVPTL PPDNGFALLE AFRADPFEKK VNLCPGIYQD ESGQTWTLPS VKKARETLLG
     NPDLKHDISP LTGHPAFVSA ARRIAFQDAL ESRHVTSMQT IAGTGANHII AQLLSDVATP
     KTVWLSDPSW ENHTKIWSHV NSKIEQRFYP YYNTETFALN DERILATLQE HAKKGDVVVL
     QACAHNPTGV DPSQEFWKKM AKLCHEKDIF PVFDLAYQGF ATGDVLNDGW AIRYFAGYAG
     GDIEFAVAQS FSKTFGLYGE RTGALHVVTR SEETANKVVG ALKKICRAEL TSTPGFGAKI
     VGTIMQDKEL ETQWYQDLKT MSDRLQDMRK KLYDQLTKRN TPGNWAHFLS DIGMFSMTGL
     SPTQLATLQD EYHIYMLPMG RLSFTGLTSS NVEYVAAAIH TAFGIKLSAN PAVIQIAANS
     GFDALFIDLE HSTLSIDDAS QLCWSGLQGG ITPFVRVPGE CGSGLVQRVL DGGAMGIIFP
     HMSSPEQAKE AVSICKYPPM GRRSMTGQLP VFGYKANAAQ TVIRHSNDSA SSVIVMIESK
     KGVDCAAEIA AVEGVDTLLV GSNDLAIELG VPGDFESTEF RSALETISEA CKKNNKIMGL
     AGIYNQPNFH DWAVAKLGVR FILGQLDVGL IAAGAVQCFA ALPVAKLP
//