ID A0A0A1T1V8_9HYPO Unreviewed; 825 AA.
AC A0A0A1T1V8;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Transcription factor BYE1 {ECO:0000256|ARBA:ARBA00021616};
GN ORFNames=VHEMI00290 {ECO:0000313|EMBL:CEJ80085.1};
OS [Torrubiella] hemipterigena.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae;
OC Clavicipitaceae incertae sedis; 'Torrubiella' clade.
OX NCBI_TaxID=1531966 {ECO:0000313|EMBL:CEJ80085.1, ECO:0000313|Proteomes:UP000039046};
RN [1] {ECO:0000313|EMBL:CEJ80085.1, ECO:0000313|Proteomes:UP000039046}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Horn F., Habel A., Scharf D.H., Dworschak J., Brakhage A.A., Guthke R.,
RA Hertweck C., Linde J.;
RT "Draft Genome Sequence and Gene Annotation of the Entomopathogenic Fungus
RT Verticillium hemipterigenum.";
RL Genome Announc. 3:e01439-e01414(2015).
CC -!- FUNCTION: Negative regulator of transcription elongation.
CC {ECO:0000256|ARBA:ARBA00002311}.
CC -!- SIMILARITY: Belongs to the BYE1 family.
CC {ECO:0000256|ARBA:ARBA00011050}.
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DR EMBL; CDHN01000001; CEJ80085.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A1T1V8; -.
DR STRING; 1531966.A0A0A1T1V8; -.
DR HOGENOM; CLU_009292_0_0_1; -.
DR OrthoDB; 5491784at2759; -.
DR Proteomes; UP000039046; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd21538; SPOC_TFIIS; 1.
DR Gene3D; 1.10.472.30; Transcription elongation factor S-II, central domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR012921; SPOC_C.
DR InterPro; IPR003618; TFIIS_cen_dom.
DR InterPro; IPR036575; TFIIS_cen_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11477:SF20; PROTEIN PARTNER OF SNF, ISOFORM B; 1.
DR PANTHER; PTHR11477; TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF20826; PHD_5; 1.
DR Pfam; PF07744; SPOC; 1.
DR Pfam; PF07500; TFIIS_M; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00510; TFS2M; 1.
DR SUPFAM; SSF46942; Elongation factor TFIIS domain 2; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51321; TFIIS_CENTRAL; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000039046};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 229..357
FT /note="TFIIS central"
FT /evidence="ECO:0000259|PROSITE:PS51321"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 122..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 653..674
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 695..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..47
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..199
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..378
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 825 AA; 90046 MW; 14A9F6DB6F00CC24 CRC64;
MSGEAEPRRS IRATKGQHTK SFDELEQAPA PKRRQSKKSR KALEQEELEQ SEEPEVIRCV
CGANEQDQDS GEAWISCETC FAWQHNVCVG VSSFEDEIPE NYWCEQCRPQ DHTELLAAMA
KGEQPWLDRR KTHEEEVANR KKKGGKRGRG KRNSDTKDDA RNAKASPTPD ASVKPAVKPG
KRKSRDESND ADGKLPKLRR VSHAESVGVQ VKYSPPPDLV TDLSQLPATR AGPIKALTKS
LVHVATALHK EGDLDIPADT TVEKIAETYA LQIERAVFDT HPSTKGQKEY AQQVKALTFN
LKNNPELFEG LVESYHSPAT LAVMTTEAMA SSEMQKQTAE MKAKAEKQSI LYTGDNGPRV
RRTHKGEEVV EDETMANNGE HRMPTSGGGA RRGGGTATPT APAIKRESIS IDHASLPAAS
PTRSDGQRSP SQSNFDISKV FSKVKSPTAT ERRRPSGPSI NVSGPGFDPE VDRLLEDETE
SPPYSPTEDT QDPDVIWKGS LAMSSIADFH AVGKHVGGAN FASFSSWSKL IPQRMTVAGR
ITEQNAIEYL CSLRYSNLTD IVVVNLTPAS PGSQPEFKAL IDYFLSKGRY GVVGNKVAGN
VRDTYLVPVR AGENGHPEFM LNLVDNFIPT TRTEDMLLAV FVYRNEPTEF SLSNNGQAAP
APLAQAPSVP GSKTTTAVPV AAAAAAAPRP IAPVPGPNGQ HARPPQPVSI PHHAQQPLPH
APAMPSKAVH QLPPNHQISS NDIYQRQQAG ERLAREILGP FISVPTAQFL LPQAFQMQQK
EWETVRGVYE RDPKAREDLK YLSMLLEKEP SKAAVPGAPA VPRAA
//
