ID A0A0A1TYA0_ENTIV Unreviewed; 288 AA.
AC A0A0A1TYA0;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 08-NOV-2023, entry version 28.
DE RecName: Full=GPN-loop GTPase 2 {ECO:0000256|RuleBase:RU365059};
GN ORFNames=EIN_032560 {ECO:0000313|EMBL:ELP86465.1};
OS Entamoeba invadens IP1.
OC Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC Entamoeba.
OX NCBI_TaxID=370355 {ECO:0000313|EMBL:ELP86465.1, ECO:0000313|Proteomes:UP000014680};
RN [1] {ECO:0000313|EMBL:ELP86465.1, ECO:0000313|Proteomes:UP000014680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP1 {ECO:0000313|EMBL:ELP86465.1,
RC ECO:0000313|Proteomes:UP000014680};
RA Zafar N., Inman J., Hall N., Lorenzi H., Caler E.;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Small GTPase required for proper localization of RNA
CC polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly
CC step prior to nuclear import. {ECO:0000256|RuleBase:RU365059}.
CC -!- SUBUNIT: Binds to RNA polymerase II (RNAPII).
CC {ECO:0000256|RuleBase:RU365059}.
CC -!- SIMILARITY: Belongs to the GPN-loop GTPase family.
CC {ECO:0000256|ARBA:ARBA00005290, ECO:0000256|RuleBase:RU365059}.
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DR EMBL; KB206969; ELP86465.1; -; Genomic_DNA.
DR RefSeq; XP_004185811.1; XM_004185763.1.
DR AlphaFoldDB; A0A0A1TYA0; -.
DR EnsemblProtists; ELP86465; ELP86465; EIN_032560.
DR GeneID; 14885384; -.
DR KEGG; eiv:EIN_032560; -.
DR VEuPathDB; AmoebaDB:EIN_032560; -.
DR OrthoDB; 168004at2759; -.
DR Proteomes; UP000014680; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004130; Gpn.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR21231:SF3; GPN-LOOP GTPASE 2; 1.
DR PANTHER; PTHR21231; XPA-BINDING PROTEIN 1-RELATED; 1.
DR Pfam; PF03029; ATP_bind_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|RuleBase:RU365059};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU365059};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU365059};
KW Reference proteome {ECO:0000313|Proteomes:UP000014680}.
SQ SEQUENCE 288 AA; 31806 MW; CD9B83896C4B6A26 CRC64;
MQTTCYGQVI TGAPGCGKTT FVKGMFSFLS LMGRTPLIVN LDPANEPSEY TDCVSLPSLL
SLDEAMTTTA LGPNGGMLYC LEYLESNVDW MLDKIAEKKA TYLLIDCPGQ TELFSTHEVL
PRILHKMLKM KFQLTAVHLI DSVHIGDPSI YIAAMLQTLA CNMNFELPFV TFLSKADLIG
NYGFKTKLDD LINGNLKDES FDLPDRLKKL SEKLAEVVDD YALIRPVPFA VEDKDDLALA
VALVDKANGY TFNSNESSVL QYFQVEGGVA VDVKIDQTIE KYQALIDG
//
