ID   A0A0A1UH53_ENTIV        Unreviewed;       722 AA.
AC   A0A0A1UH53;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=J domain-containing protein {ECO:0000259|PROSITE:PS50076};
GN   ORFNames=EIN_340590 {ECO:0000313|EMBL:ELP94721.1};
OS   Entamoeba invadens IP1.
OC   Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC   Entamoeba.
OX   NCBI_TaxID=370355 {ECO:0000313|EMBL:ELP94721.1, ECO:0000313|Proteomes:UP000014680};
RN   [1] {ECO:0000313|EMBL:ELP94721.1, ECO:0000313|Proteomes:UP000014680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP1 {ECO:0000313|EMBL:ELP94721.1,
RC   ECO:0000313|Proteomes:UP000014680};
RA   Zafar N., Inman J., Hall N., Lorenzi H., Caler E.;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; KB206175; ELP94721.1; -; Genomic_DNA.
DR   RefSeq; XP_004261492.1; XM_004261444.1.
DR   AlphaFoldDB; A0A0A1UH53; -.
DR   EnsemblProtists; ELP94721; ELP94721; EIN_340590.
DR   GeneID; 14893699; -.
DR   KEGG; eiv:EIN_340590; -.
DR   VEuPathDB; AmoebaDB:EIN_340590; -.
DR   OrthoDB; 1605at2759; -.
DR   Proteomes; UP000014680; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd06257; DnaJ; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   Gene3D; 1.10.287.110; DnaJ domain; 1.
DR   Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR036869; J_dom_sf.
DR   InterPro; IPR004179; Sec63-dom.
DR   PANTHER; PTHR24075; SEC63 DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR24075:SF0; TRANSLOCATION PROTEIN SEC63 HOMOLOG; 1.
DR   Pfam; PF00226; DnaJ; 1.
DR   Pfam; PF02889; Sec63; 1.
DR   PRINTS; PR00625; JDOMAIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SMART; SM00973; Sec63; 1.
DR   SUPFAM; SSF46565; Chaperone J-domain; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
PE   4: Predicted;
KW   Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014680};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        64..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        192..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          102..166
FT                   /note="J"
FT                   /evidence="ECO:0000259|PROSITE:PS50076"
FT   REGION          692..722
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        698..712
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   722 AA;  83375 MW;  66376FF66A8F1789 CRC64;
     MSEEKPIFDD QMFQVFLTGL SGTIVVLWVL YLLRQRIKVL PSFPCTCSRC LEKKAKLTRR
     RNRLTGSLCL QLFFIFLLTL LFLRGAYKTV TTPVGTPTVL YDPYTILEVS QTSSDKDIRS
     SYRKLSLKYH PDKNKSPEAE EKFIQITKAY ETLTDPLKLK LWRETGNEEE KRIEKNGIGL
     PMFLTLQKNR TVVLGFYFFI VVILFPIGVW LLLRKFHNYD NNNLTLETNA IFMQLIDTNL
     TFPTLIEVLT LSNEITEIVT IKPDDQKYLP AIQKRVNSLF IKTPKYNSPQ AVKAQILLAA
     HLTRLHNELP YYLRDDLDEI LQVVPNILHG MVSVMFSKRN LNGVWQCIRL NQMVTQATDI
     EFNQIPEDVD SKLFGKNMTF EKFCRLTPED RKRLIEDRVV DGIDKSKDVK LIQPLKEKSE
     VKKMKLETVK EKIKQSINEK DKKMGKKPRF EAVEEHCSIQ SKEIKEKSDL ALQDQSHKTD
     TNAFKPLTVE AKTRQKVILN YFNYFPTTID FVVRAMSATM TRTVIAGIPL VIVINAYRYP
     RGQDGEVLPK LRGKLQKILD AEKEDLPVEP QSAEELLKRP TEEQEDDVDP VIPDVEIVHA
     PPQDVYVHCP YCPNERLERW WFILTDMRNS VVLNAAHGYI PVSELPFITR VFAPTPKQAG
     NYAVSLHIVC DSYMGCSRVF PLNFTVVERK KSAEEDLVNG EEEEEEMESD DVESSEDAKK
     DK
//