ID   A0A0A1USZ8_9HYPO        Unreviewed;       718 AA.
AC   A0A0A1USZ8;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Heat-labile enterotoxin alpha chain {ECO:0000313|EMBL:EXU99100.1};
GN   ORFNames=X797_007823 {ECO:0000313|EMBL:EXU99100.1};
OS   Metarhizium robertsii.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX   NCBI_TaxID=568076 {ECO:0000313|EMBL:EXU99100.1, ECO:0000313|Proteomes:UP000030151};
RN   [1] {ECO:0000313|EMBL:EXU99100.1, ECO:0000313|Proteomes:UP000030151}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ARSEF 2575 {ECO:0000313|EMBL:EXU99100.1,
RC   ECO:0000313|Proteomes:UP000030151};
RA   Giuliano Garisto Donzelli B., Roe B.A., Macmil S.L., Krasnoff S.B.,
RA   Gibson D.M.;
RT   "The genome sequence of the entomopathogenic fungus Metarhizium robertsii
RT   ARSEF 2575.";
RL   Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EXU99100.1}.
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DR   EMBL; JELW01000021; EXU99100.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0A1USZ8; -.
DR   eggNOG; ENOG502S2GC; Eukaryota.
DR   HOGENOM; CLU_384985_0_0_1; -.
DR   OrthoDB; 2488279at2759; -.
DR   Proteomes; UP000030151; Unassembled WGS sequence.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.20.10; Crystallins; 1.
DR   Gene3D; 3.90.210.10; Heat-Labile Enterotoxin, subunit A; 1.
DR   InterPro; IPR046533; DUF6598.
DR   InterPro; IPR001144; Enterotoxin_A.
DR   Pfam; PF20241; DUF6598; 1.
DR   Pfam; PF01375; Enterotoxin_a; 1.
DR   PRINTS; PR00771; ENTEROTOXINA.
DR   SUPFAM; SSF56399; ADP-ribosylation; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Toxin {ECO:0000256|ARBA:ARBA00022656};
KW   Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..718
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001980832"
FT   DOMAIN          467..707
FT                   /note="DUF6598"
FT                   /evidence="ECO:0000259|Pfam:PF20241"
FT   REGION          29..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          202..222
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   718 AA;  78611 MW;  0F8438CE68C87776 CRC64;
     MNGQNALSLL LAAIFFFFCH VQGAPPPATP GGIRARAPGK PPFVWRGETG KTRDGKPGRS
     PADVQRAGGM WARGFQIIDQ LSPEQLEAGS GLWTHTNNPG GTRDVTQYVS TSTSLIGAIT
     FAVRPSPEHA QEVGYLYRIR TNWAMVDVNL SLENISPYPE QQEQAAVQGI PWNQILGWYE
     VRAADLNRIL GAEDPISQLG RFTRNPDFRP DSTDPSGAQP QLAGLQNPVE GRHGAWEAYV
     GQSVASNLRQ FIREYGPQTE AADQTTLSSL DWSAVEIPAH LRTALGQGAA SAAQCAMALA
     AVVVSWHHDE LKRSIPWHKV DGRDTTSNLG SNACGRLATA VKDKAENKEA TVKICDEPQS
     GGECLTIQTP PQSCVGVPLE WNDRASTILL SASAGICQFF HDYNCAGASF QSSFPGNDRL
     DEFDEGRFNN MISSIRCDNT SPETQIERPP VIEVAKPDAC IAKPRPLAEI LWVMINNIDG
     ENPGDLFGSI HATDDSGRQV IYNVEKDDSV SVEPRDQITL RTSRPLAADG NFVIDLDLWD
     RDRDASPHDE VSRGRIAWKV YDPANEYDTP IQTEVDGEYG KATVDYVVMS SATQAVVQVI
     MLDGDGEKPA DVFGRIRTSS RFVQRDLFNR EGGDSIEIYP GTAIPLSRAI MAVPMLDTLK
     IHVDLWDHDA DWSPNDQIAY GIAEFRPQLS GSEKRVVDGE YGKVEVWVTW GGDRPQGC
//