ID A0A0A1UT32_9HYPO Unreviewed; 863 AA.
AC A0A0A1UT32;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Negative regulator of quinate utilization {ECO:0000313|EMBL:EXU98987.1};
GN ORFNames=X797_007985 {ECO:0000313|EMBL:EXU98987.1};
OS Metarhizium robertsii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=568076 {ECO:0000313|EMBL:EXU98987.1, ECO:0000313|Proteomes:UP000030151};
RN [1] {ECO:0000313|EMBL:EXU98987.1, ECO:0000313|Proteomes:UP000030151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 2575 {ECO:0000313|EMBL:EXU98987.1,
RC ECO:0000313|Proteomes:UP000030151};
RA Giuliano Garisto Donzelli B., Roe B.A., Macmil S.L., Krasnoff S.B.,
RA Gibson D.M.;
RT "The genome sequence of the entomopathogenic fungus Metarhizium robertsii
RT ARSEF 2575.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the 2nd section; belongs to the type-I 3-dehydroquinase
CC family. {ECO:0000256|ARBA:ARBA00006477}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the shikimate kinase
CC family. {ECO:0000256|ARBA:ARBA00009349}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXU98987.1}.
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DR EMBL; JELW01000022; EXU98987.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A1UT32; -.
DR eggNOG; KOG0692; Eukaryota.
DR HOGENOM; CLU_008871_0_1_1; -.
DR OrthoDB; 2256238at2759; -.
DR Proteomes; UP000030151; Unassembled WGS sequence.
DR GO; GO:0003855; F:3-dehydroquinate dehydratase activity; IEA:InterPro.
DR GO; GO:0004764; F:shikimate 3-dehydrogenase (NADP+) activity; IEA:InterPro.
DR CDD; cd00502; DHQase_I; 1.
DR CDD; cd01065; NAD_bind_Shikimate_DH; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.40.50.10860; Leucine Dehydrogenase, chain A, domain 1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR046346; Aminoacid_DH-like_N_sf.
DR InterPro; IPR001381; DHquinase_I.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041121; SDH_C.
DR InterPro; IPR031322; Shikimate/glucono_kinase.
DR InterPro; IPR013708; Shikimate_DH-bd_N.
DR InterPro; IPR006151; Shikm_DH/Glu-tRNA_Rdtase.
DR PANTHER; PTHR21090; AROM/DEHYDROQUINATE SYNTHASE; 1.
DR PANTHER; PTHR21090:SF27; QUINATE REPRESSOR PROTEIN; 1.
DR Pfam; PF01487; DHquinase_I; 1.
DR Pfam; PF18317; SDH_C; 1.
DR Pfam; PF01488; Shikimate_DH; 1.
DR Pfam; PF08501; Shikimate_dh_N; 1.
DR Pfam; PF01202; SKI; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR SUPFAM; SSF53223; Aminoacid dehydrogenase-like, N-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
FT DOMAIN 525..605
FT /note="Shikimate dehydrogenase substrate binding N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08501"
FT DOMAIN 668..719
FT /note="Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA
FT reductase"
FT /evidence="ECO:0000259|Pfam:PF01488"
FT DOMAIN 809..838
FT /note="SDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18317"
FT REGION 15..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 863 AA; 95434 MW; AFDE554353ECF2EC CRC64;
MAGVKRSLAA MMADERSLSL GDTTEPITRP RSAKTSVNSS EYTSEAPSPT LPPLNGHMPR
FSPDASIVIV GVRGAGKTTL AIMAASALKK RIVDLEGAFQ RATNFSSPTY SKVHGTTQCQ
IKQGDVLQSI LETNTTGCII VCSWMERRVQ GLLRQFAASN PVVHVMRSKE AVQEHLRVES
GTKWETFWST SNAFFRTCSN LEFFNVSESA AVEKSLSSLR NSNGVDLPPY LALKQAERHL
LKFFSQIYPA GTIPFFESAY PLASVATEQR QYTYAVDISV EEIIHNRVDI EDCSAGADAM
QITLEDIQID WAHCRYLDEH TKMANRVTEA VGLVRRSSVL PIIVHIGFPN PSAATTSTYF
YLDLLSHVLT LAPEMMTVDL RLDDNAIAKL ASLKRSCKLI GHYAPIANFD SWTSPQWISH
YQRAVRLDCD LVRFVRPAEA VTDNFEVARF RSTVESLPDS HAPIIAYNSG NLGKHSAFLN
PILTSVSPRL ESQNNEKQRQ TGLLADSATR ALYASFLFDP MKLYVFGANV GYSMSPAMHN
SALEVCGVPH RYEPYSTNSL QQVRHLIQDP NFAGASIGLP FKVEFITLTD SLSPHAQAIG
AINTLIPIRH LNDDGTVPTG AASFFRGVNR AGPVLALYGE NTDWIGIRSC IRRGLSPANA
VRPATCGLVI GAGGMARAAV YALLQVGVSN IAIYNRTVEN GKKLADHFTQ LLQKREFEGL
GAGVKTKFEV LPTLHHDWQS EFRLPSIIIS CIPTHPIGDV PSPEFRLPES WLENQTGGVI
VELGYKTLNT PLLQQAMEHA SRRWIAMDGL DLLPDQGFAQ FELFTGKRAP RKTMKKAIFE
NYPDQYGRSN PEELRRRLQT MLE
//
