ID A0A0A1VDX4_9BURK Unreviewed; 143 AA.
AC A0A0A1VDX4;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Cytochrome bo(3) ubiquinol oxidase subunit 4 {ECO:0000256|ARBA:ARBA00014689};
DE AltName: Full=Cytochrome o ubiquinol oxidase subunit 4 {ECO:0000256|ARBA:ARBA00032185};
DE AltName: Full=Oxidase bo(3) subunit 4 {ECO:0000256|ARBA:ARBA00030071};
DE AltName: Full=Ubiquinol oxidase polypeptide IV {ECO:0000256|ARBA:ARBA00030211};
DE AltName: Full=Ubiquinol oxidase subunit 4 {ECO:0000256|ARBA:ARBA00031887};
GN ORFNames=AVS7_01129 {ECO:0000313|EMBL:GAD21369.1};
OS Acidovorax sp. MR-S7.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Acidovorax.
OX NCBI_TaxID=1268622 {ECO:0000313|EMBL:GAD21369.1};
RN [1] {ECO:0000313|EMBL:GAD21369.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR-S7 {ECO:0000313|EMBL:GAD21369.1};
RX DOI=10.1128/genomeA.00412-13;
RA Miura T., Kusada H., Kamagata Y., Hanada S., Kimura N.;
RT "Genome Sequence of the Multiple-beta-Lactam-Antibiotic-Resistant Bacterium
RT Acidovorax sp. Strain MR-S7.";
RL Genome Announc. 1:e00412-13(2013).
CC -!- FUNCTION: Cytochrome bo(3) ubiquinol terminal oxidase is the component
CC of the aerobic respiratory chain of E.coli that predominates when cells
CC are grown at high aeration. Has proton pump activity across the
CC membrane in addition to electron transfer, pumping 2 protons/electron.
CC {ECO:0000256|ARBA:ARBA00025694}.
CC -!- SUBUNIT: Heterooctamer of two A chains, two B chains, two C chains and
CC two D chains. {ECO:0000256|ARBA:ARBA00011700}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the cytochrome c oxidase bacterial subunit 4
CC family. {ECO:0000256|ARBA:ARBA00008079}.
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DR EMBL; DF238903; GAD21369.1; -; Genomic_DNA.
DR RefSeq; WP_020227424.1; NZ_DF238903.1.
DR AlphaFoldDB; A0A0A1VDX4; -.
DR STRING; 1268622.AVS7_01129; -.
DR eggNOG; COG3125; Bacteria.
DR OrthoDB; 2375888at2; -.
DR Proteomes; UP000030646; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0009486; F:cytochrome bo3 ubiquinol oxidase activity; IEA:InterPro.
DR GO; GO:0015990; P:electron transport coupled proton transport; IEA:InterPro.
DR InterPro; IPR005171; Cyt_c_oxidase_su4_prok.
DR InterPro; IPR014210; Cyt_o_ubiqinol_oxidase_su4.
DR NCBIfam; TIGR02847; CyoD; 1.
DR PANTHER; PTHR36835; CYTOCHROME BO(3) UBIQUINOL OXIDASE SUBUNIT 4; 1.
DR PANTHER; PTHR36835:SF1; CYTOCHROME BO(3) UBIQUINOL OXIDASE SUBUNIT 4; 1.
DR Pfam; PF03626; COX4_pro; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030646};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 143 AA; 15638 MW; 0DD4AC76BAFDFA98 CRC64;
MSAHELHAGH GGDHHDDHHG HGDDLHVTRS DYIKGFVLAV ILTAIPFWLV MAGVIQNRTT
AVLVLGVLAA VQIVVHMVYF LHMNGKIQGG WTMLSTLFTI VFVAVTLAGT LWVMFHMNAN
MMPSHANPMT GQPQVGEHHH TAP
//
