ID A0A0A2L5H7_PENIT Unreviewed; 355 AA.
AC A0A0A2L5H7;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 03-MAY-2023, entry version 21.
DE SubName: Full=Polyketide synthase, enoylreductase {ECO:0000313|EMBL:KGO74416.1};
GN ORFNames=PITC_019490 {ECO:0000313|EMBL:KGO74416.1};
OS Penicillium italicum (Blue mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=40296 {ECO:0000313|EMBL:KGO74416.1, ECO:0000313|Proteomes:UP000030104};
RN [1] {ECO:0000313|EMBL:KGO74416.1, ECO:0000313|Proteomes:UP000030104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHI-1 {ECO:0000313|EMBL:KGO74416.1,
RC ECO:0000313|Proteomes:UP000030104};
RX PubMed=25338147; DOI=10.1094/MPMI-09-14-0261-FI;
RA Ballester A.R., Marcet-Houben M., Levin E., Sela N., Selma-Lazaro C.,
RA Carmona L., Wisniewski M., Droby S., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome, transcriptome, and functional analyses of Penicillium expansum
RT provide new insights into secondary metabolism and pathogenicity.";
RL Mol. Plant Microbe Interact. 28:232-248(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGO74416.1}.
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DR EMBL; JQGA01000620; KGO74416.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A2L5H7; -.
DR STRING; 40296.A0A0A2L5H7; -.
DR HOGENOM; CLU_026673_3_3_1; -.
DR OMA; VIAFQNI; -.
DR OrthoDB; 2127369at2759; -.
DR PhylomeDB; A0A0A2L5H7; -.
DR Proteomes; UP000030104; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd08267; MDR1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43482; PROTEIN AST1-RELATED; 1.
DR PANTHER; PTHR43482:SF1; PROTEIN AST1-RELATED; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030104}.
FT DOMAIN 24..350
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 355 AA; 38165 MW; F50BB0F433F806A2 CRC64;
MSSKTQLPTV PPTMRAWVRR RRGSADRALE LVTDYPTPDV PTGSSPDVLI RVSNVPLQFS
SEMIMKTLPI LPFTSPWVPE IELSGVVVAA GGGAPAEVRD PGSHVIAFQN IPSAVVMGHG
VLAEYVRLPG CQVTRINDGI DMVSASGIIG SGSTALKMIR TVGVREGHTV LVNGASGSVG
SVLVQLCKLR GAKVVGVASG GNEPMVRDLG VDEFIDYREH EPLPAYLAHR YGNKPFDFIL
DCVGTQALFV NSPAYLKPEG AVVNIGMLEG MFVTASNVLL NSWLPIWLGG VPRRYVSFST
PPAIDDAVYL ARLIEEGHLR IPVDSVFEMK DALFAYERIA TKRARGKVVV KVHGD
//
