ID A0A0A2LT76_9FLAO Unreviewed; 635 AA.
AC A0A0A2LT76;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=Q763_02930 {ECO:0000313|EMBL:KGO83537.1};
OS Flavobacterium beibuense F44-8.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1406840 {ECO:0000313|EMBL:KGO83537.1, ECO:0000313|Proteomes:UP000030129};
RN [1] {ECO:0000313|EMBL:KGO83537.1, ECO:0000313|Proteomes:UP000030129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F44-8 {ECO:0000313|EMBL:KGO83537.1,
RC ECO:0000313|Proteomes:UP000030129};
RA Zeng Z., Chen C.;
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGO83537.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JRLV01000003; KGO83537.1; -; Genomic_DNA.
DR RefSeq; WP_035130993.1; NZ_JRLV01000003.1.
DR AlphaFoldDB; A0A0A2LT76; -.
DR STRING; 1406840.Q763_02930; -.
DR eggNOG; COG0365; Bacteria.
DR Proteomes; UP000030129; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:KGO83537.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030129}.
FT DOMAIN 12..68
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 70..463
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 519..598
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 635 AA; 72255 MW; 1FA7F9DAC38537C5 CRC64;
MSYYQIKSLE QYFKHYNKSI REPRKFWDKI ADENFTWYQK WDKVVEFDMQ EAEVKWFLNA
KVNITKNCID RHLAKRGEKT AIIFEPNNPD EEAQHITYNE LYERVTKMAN VLRDQGVKKG
DRVCIYLPMI PELAITVLAC ARIGAVHSVI FAGFSASAVT SRVLDLQCKL VVTSDGGFRG
NKTIDLKGII DEALEKCPCV EKTLVVKRTN SKVNMKEGRD YWLQPLLDSA PSNNVAEIMD
AEDPLFILYT SGSTGKPKGM MHTTAGYMVY SAYTFKNIFN YEENDVYWCT ADIGWITGHS
YIVYGPLLNG ATTVIFEGVP SYPDFGRFWE IIDKHKVTQF YTAPTAIRSL AKENWEWVDK
YDLSSLKIIG SVGEPINEEA WHWYNDHVGK KKSPIVDTWW QTETGGIMIS PIPFVTPTKP
TYATLPLPGV QPVLMDERRN EIEDNQVVGS LCIKFPWPGM ARTIWGDHQR FKETYFTAFP
GKYFTGDGAL RDEVGYYRIT GRVDDVVIVS GHNLGTAPIE DAINEHPAVA ESAIVGFPHE
VKGNALYGFI TLKESGEDRN RDNLRKEINE HISSHIGPIA KLDKIQFVSG LPKTRSGKIM
RRILRKIAEG DFSNFGDTTT LLNPEIVDEI KNERI
//
