ID   A0A0A5G5F2_9BACI        Unreviewed;       814 AA.
AC   A0A0A5G5F2;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=N784_05085 {ECO:0000313|EMBL:KGX86325.1};
OS   Pontibacillus litoralis JSM 072002.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Pontibacillus.
OX   NCBI_TaxID=1385512 {ECO:0000313|EMBL:KGX86325.1, ECO:0000313|Proteomes:UP000030401};
RN   [1] {ECO:0000313|EMBL:KGX86325.1, ECO:0000313|Proteomes:UP000030401}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JSM 072002 {ECO:0000313|EMBL:KGX86325.1,
RC   ECO:0000313|Proteomes:UP000030401};
RA   Huang J., Wang G.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGX86325.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AVPG01000014; KGX86325.1; -; Genomic_DNA.
DR   RefSeq; WP_036834561.1; NZ_AVPG01000014.1.
DR   AlphaFoldDB; A0A0A5G5F2; -.
DR   STRING; 1385512.N784_05085; -.
DR   eggNOG; COG5001; Bacteria.
DR   Proteomes; UP000030401; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 2.10.70.100; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR018000; Neurotransmitter_ion_chnl_CS.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 2.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 2.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS00236; NEUROTR_ION_CHANNEL; 1.
DR   PROSITE; PS50113; PAC; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030401}.
FT   DOMAIN          208..260
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          336..388
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          416..548
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          557..810
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   814 AA;  94764 MW;  06AA4DE6A025EAC2 CRC64;
     MERRKGSSVE QEDTLWQHIA DNHKVSGGIE WIASYVYAST IPTYILNRER KVVMCNQKDL
     IDEIYRDQPT LLADFRNAIH GELTCTTITI NDGTIADVKH VPLKVQGEVQ SVIMTLHDVT
     DVHQLQAELQ MEKTHLYYSQ QIAKVGSWDY DVLKDKMNSS AYHYYLYGFN DKQAAEVESD
     WFFNRIHPDD QERMKQVVEH TFCTGEAQHV QYRIQRINDE RTLTIESDIY AIKEQGQVVR
     LFGVVYDITE YDQMRKELNK QNERITNIYN SLNVGVWAFD YLNNQVTFCS EGVQHLYETP
     TEAFQNDPFL WKKCIYPDDR QRVLDMQAPL HVGQEINHEY RIVTSTGKVR WVKDQTIPKV
     DENGELVSLM GIMLDITDRK LYEQKLEHSI RHDRLSKLGN GYYLEETFQK QVMQQQPMAL
     FLIEVQRMKE MKESFGYALK DEVIQMIARR LEKGFPAPFI LARISDDELV ALVKHGSDEA
     MVDRCERVHN EIKKEMTVQG YRLQISCNIG VSFYPRDGET CDEVLQSARK ACNRGKESGQ
     DRYFFYPNSD DAICFKQIAI ERDLRHAIKF NQFELHYQPK VDIQGTLQGA EALIRWNHPE
     LGVIPPSEFI PIAEEGDFII DIGNWVIAEV CRQLQDWSRR GFPLCPVSFN ISPVHLYKQH
     LICTIKGELR KHNVHGKWLE MELTETSFMN ETLVNQLAKE LKKLGMKMTI DDFGVGFTSL
     QYFQRIDRDK VKIDKSYIQG LNEGKGQNNI IVSSIIQLSH DLETKVVAEG VETIEQYEFL
     KAKQVDELQG FYFARPLPVS QFEPILQKRK VVHS
//