ID A0A0A6YYL6_HUMAN Unreviewed; 228 AA.
AC A0A0A6YYL6;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Large ribosomal subunit protein uL22 {ECO:0000256|ARBA:ARBA00035207};
DE AltName: Full=60S ribosomal protein L17 {ECO:0000256|ARBA:ARBA00035325};
GN Name=RPL17-C18orf32 {ECO:0000313|Ensembl:ENSP00000463379};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000463379, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000463379, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16177791; DOI=10.1038/nature03983;
RA Nusbaum C., Zody M.C., Borowsky M.L., Kamal M., Kodira C.D., Taylor T.D.,
RA Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X.,
RA Abouelleil A., Allen N.R., Anderson S., Bloom T., Bugalter B., Butler J.,
RA Cook A., DeCaprio D., Engels R., Garber M., Gnirke A., Hafez N., Hall J.L.,
RA Norman C.H., Itoh T., Jaffe D.B., Kuroki Y., Lehoczky J., Lui A.,
RA Macdonald P., Mauceli E., Mikkelsen T.S., Naylor J.W., Nicol R., Nguyen C.,
RA Noguchi H., O'Leary S.B., O'Neill K., Piqani B., Smith C.L., Talamas J.A.,
RA Topham K., Totoki Y., Toyoda A., Wain H.M., Young S.K., Zeng Q.,
RA Zimmer A.R., Fujiyama A., Hattori M., Birren B.W., Sakaki Y., Lander E.S.;
RT "DNA sequence and analysis of human chromosome 18.";
RL Nature 437:551-555(2005).
RN [2] {ECO:0000313|Ensembl:ENSP00000463379}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (DEC-2014) to UniProtKB.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL22 family.
CC {ECO:0000256|ARBA:ARBA00009451, ECO:0000256|RuleBase:RU004005}.
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DR EMBL; AC100778; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001186284.1; NM_001199355.1.
DR AlphaFoldDB; A0A0A6YYL6; -.
DR SMR; A0A0A6YYL6; -.
DR IntAct; A0A0A6YYL6; 2.
DR STRING; 9606.ENSP00000463379; -.
DR MetOSite; A0A0A6YYL6; -.
DR BioMuta; RPL17-C18orf32; -.
DR MassIVE; A0A0A6YYL6; -.
DR PaxDb; 9606-ENSP00000463379; -.
DR Antibodypedia; 22602; 31 antibodies from 9 providers.
DR DNASU; 100526842; -.
DR Ensembl; ENST00000584895; ENSP00000463379; ENSG00000215472.
DR GeneID; 100526842; -.
DR KEGG; hsa:100526842; -.
DR AGR; HGNC:44661; -.
DR CTD; 100526842; -.
DR GeneCards; RPL17-C18orf32; -.
DR HGNC; HGNC:44661; RPL17-C18orf32.
DR VEuPathDB; HostDB:ENSG00000215472; -.
DR eggNOG; KOG3353; Eukaryota.
DR OrthoDB; 5479326at2759; -.
DR PhylomeDB; A0A0A6YYL6; -.
DR BioGRID-ORCS; 100526842; 352 hits in 657 CRISPR screens.
DR ChiTaRS; RPL17-C18orf32; human.
DR GenomeRNAi; 100526842; -.
DR Proteomes; UP000005640; Chromosome 18.
DR RNAct; A0A0A6YYL6; Protein.
DR Bgee; ENSG00000215472; Expressed in C1 segment of cervical spinal cord and 103 other cell types or tissues.
DR ExpressionAtlas; A0A0A6YYL6; baseline and differential.
DR GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd00336; Ribosomal_L22; 1.
DR Gene3D; 3.90.470.10; Ribosomal protein L22/L17; 1.
DR HAMAP; MF_01331_A; Ribosomal_L22_A; 1.
DR InterPro; IPR001063; Ribosomal_uL22.
DR InterPro; IPR018260; Ribosomal_uL22_CS.
DR InterPro; IPR005721; Ribosomal_uL22_euk/arc.
DR InterPro; IPR036394; Ribosomal_uL22_sf.
DR NCBIfam; TIGR01038; uL22_arch_euk; 1.
DR PANTHER; PTHR11593; 60S RIBOSOMAL PROTEIN L17; 1.
DR PANTHER; PTHR11593:SF11; 60S RIBOSOMAL PROTEIN L17; 1.
DR Pfam; PF00237; Ribosomal_L22; 1.
DR SUPFAM; SSF54843; Ribosomal protein L22; 1.
DR PROSITE; PS00464; RIBOSOMAL_L22; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU004005};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980,
KW ECO:0000256|RuleBase:RU004005}.
SQ SEQUENCE 228 AA; 26373 MW; DF45454F21504C77 CRC64;
MVRYSLDPEN PTKSCKSRGS NLRVHFKNTR ETAQAIKGMH IRKATKYLKD VTLQKQCVPF
RRYNGGVGRC AQAKQWGWTQ GRWPKKSAEF LLHMLKNAES NAELKGLDVD SLVIEHIQVN
KAPKMRRRTY RAHGRINPYM SSPCHIEMIL TEKEQIVPKP EEEVAQKKKL RSSSLGKWCA
FLVSSFQFCS GSTKNSWSHI YTLWFPPSLV VYGLRKQYKN PMIQTKAK
//
