ID A0A0A7V7N4_9ARCH Unreviewed; 358 AA.
AC A0A0A7V7N4;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Alcohol dehydrogenase, catalytic domain, GroES-like family {ECO:0000313|EMBL:AJA92655.1};
DE SubName: Full=Zn-dependent oxidoreductase {ECO:0000313|EMBL:PTL87150.1};
GN ORFNames=A7X95_04325 {ECO:0000313|EMBL:PTL87150.1}, T478_1333
GN {ECO:0000313|EMBL:AJA92655.1};
OS Candidatus Nitrosopelagicus brevis.
OC Archaea; Nitrososphaerota.
OX NCBI_TaxID=1410606 {ECO:0000313|EMBL:AJA92655.1, ECO:0000313|Proteomes:UP000030944};
RN [1] {ECO:0000313|EMBL:AJA92655.1, ECO:0000313|Proteomes:UP000030944}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CN25 {ECO:0000313|EMBL:AJA92655.1}, and V2
RC {ECO:0000313|Proteomes:UP000030944};
RX PubMed=25587132; DOI=10.1073/pnas.1416223112;
RA Santoro A.E., Dupont C.L., Richter R.A., Craig M.T., Carini P.,
RA McIlvin M.R., Yang Y., Orsi W.D., Moran D.M., Saito M.A.;
RT "Genomic and proteomic characterization of "Candidatus Nitrosopelagicus
RT brevis": An ammonia-oxidizing archaeon from the open ocean.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:1173-1178(2015).
RN [2] {ECO:0000313|EMBL:PTL87150.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=U25 {ECO:0000313|EMBL:PTL87150.1};
RA Lavstsen T., Jespersen J.S.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000241022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=U25 {ECO:0000313|Proteomes:UP000241022};
RA Dupont C., Santoro A.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:PTL87150.1, ECO:0000313|Proteomes:UP000241022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=U25 {ECO:0000313|EMBL:PTL87150.1,
RC ECO:0000313|Proteomes:UP000241022};
RA Carini P.;
RT "Transcriptomics of ammonia oxidizing archaea.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072}.
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DR EMBL; CP007026; AJA92655.1; -; Genomic_DNA.
DR EMBL; LXWN01000002; PTL87150.1; -; Genomic_DNA.
DR RefSeq; WP_048106242.1; NZ_LXWN01000002.1.
DR STRING; 1410606.T478_1333; -.
DR GeneID; 24817212; -.
DR KEGG; nbv:T478_1333; -.
DR HOGENOM; CLU_026673_3_4_2; -.
DR OrthoDB; 8709at2157; -.
DR Proteomes; UP000030944; Chromosome.
DR Proteomes; UP000241022; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd08266; Zn_ADH_like1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR44154; QUINONE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR44154:SF1; QUINONE OXIDOREDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030944}.
FT DOMAIN 17..353
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 358 AA; 38797 MW; DF80D21AB264B2FA CRC64;
MKAVVYREYA PDDNYAKILK VEDIDSPKPK PDEVVFTNKA SALNYNDIWG MRGVPIAIPL
PHVSGSDVAG DVIAVGEDVK GFKVGDRVVS HSNLACRVCS ACTSGREFDC TRRQVWGFQT
GPLWGAYSEE VHLPEVNVSH IPEGVSYEDA AAASMTILTS WHMLVGRAKI TPGQTVLVMG
GGSGVGSFAI QIAKLYNCDV IATASPDKLD KCLELGADHA VDHRQEDWSK QVFKISKEIA
KTKGQAPGID LSFDHIGETH FNKQLQLLKY GATLVSCGAT TGYDAKIDLR HIFFKGINVL
GSTQGTKAEL DEGLYWMGQG KIKAAVDSVY TFEQAAEAHT KMLSGKFFGK ILLKPEGA
//
