ID A0A0A8B524_9ACTN Unreviewed; 418 AA.
AC A0A0A8B524;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Molybdopterin molybdenumtransferase {ECO:0000256|RuleBase:RU365090};
DE EC=2.10.1.1 {ECO:0000256|RuleBase:RU365090};
GN ORFNames=JI75_07040 {ECO:0000313|EMBL:AJC12454.1};
OS Berryella intestinalis.
OC Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC Berryella.
OX NCBI_TaxID=1531429 {ECO:0000313|EMBL:AJC12454.1, ECO:0000313|Proteomes:UP000031121};
RN [1] {ECO:0000313|Proteomes:UP000031121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=68-1-3 {ECO:0000313|Proteomes:UP000031121};
RA Looft T., Bayles D.O., Stanton T.B.;
RT "Coriobacteriaceae sp. complete genome.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AJC12454.1, ECO:0000313|Proteomes:UP000031121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=68-1-3 {ECO:0000313|EMBL:AJC12454.1,
RC ECO:0000313|Proteomes:UP000031121};
RX PubMed=26450725;
RA Looft T., Bayles D.O., Alt D.P., Stanton T.B.;
RT "Complete Genome Sequence of Coriobacteriaceae Strain 68-1-3, a Novel
RT Mucus-Degrading Isolate from the Swine Intestinal Tract.";
RL Genome Announc. 3:e01143-15(2015).
CC -!- FUNCTION: Catalyzes the insertion of molybdate into adenylated
CC molybdopterin with the concomitant release of AMP.
CC {ECO:0000256|ARBA:ARBA00002901, ECO:0000256|RuleBase:RU365090}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-
CC molybdopterin; Xref=Rhea:RHEA:35047, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:36264, ChEBI:CHEBI:62727,
CC ChEBI:CHEBI:71302, ChEBI:CHEBI:456215; EC=2.10.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001529};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU365090};
CC -!- PATHWAY: Cofactor biosynthesis; molybdopterin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005046, ECO:0000256|RuleBase:RU365090}.
CC -!- SIMILARITY: Belongs to the MoeA family. {ECO:0000256|ARBA:ARBA00010763,
CC ECO:0000256|RuleBase:RU365090}.
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DR EMBL; CP009302; AJC12454.1; -; Genomic_DNA.
DR RefSeq; WP_039690737.1; NZ_CP009302.1.
DR AlphaFoldDB; A0A0A8B524; -.
DR STRING; 1531429.JI75_07040; -.
DR KEGG; cbac:JI75_07040; -.
DR HOGENOM; CLU_010186_7_0_11; -.
DR OrthoDB; 9804758at2; -.
DR UniPathway; UPA00344; -.
DR Proteomes; UP000031121; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0061599; F:molybdopterin molybdotransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd00887; MoeA; 1.
DR Gene3D; 3.40.980.10; MoaB/Mog-like domain; 1.
DR Gene3D; 2.40.340.10; MoeA, C-terminal, domain IV; 1.
DR Gene3D; 3.90.105.10; Molybdopterin biosynthesis moea protein, domain 2; 1.
DR Gene3D; 2.170.190.11; Molybdopterin biosynthesis moea protein, domain 3; 1.
DR InterPro; IPR036425; MoaB/Mog-like_dom_sf.
DR InterPro; IPR001453; MoaB/Mog_dom.
DR InterPro; IPR038987; MoeA-like.
DR InterPro; IPR005111; MoeA_C_domain_IV.
DR InterPro; IPR036688; MoeA_C_domain_IV_sf.
DR InterPro; IPR005110; MoeA_linker/N.
DR InterPro; IPR036135; MoeA_linker/N_sf.
DR NCBIfam; TIGR00177; molyb_syn; 1.
DR PANTHER; PTHR10192:SF5; GEPHYRIN; 1.
DR PANTHER; PTHR10192; MOLYBDOPTERIN BIOSYNTHESIS PROTEIN; 1.
DR Pfam; PF00994; MoCF_biosynth; 1.
DR Pfam; PF03454; MoeA_C; 1.
DR Pfam; PF03453; MoeA_N; 1.
DR SMART; SM00852; MoCF_biosynth; 1.
DR SUPFAM; SSF63867; MoeA C-terminal domain-like; 1.
DR SUPFAM; SSF63882; MoeA N-terminal region -like; 1.
DR SUPFAM; SSF53218; Molybdenum cofactor biosynthesis proteins; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|RuleBase:RU365090};
KW Metal-binding {ECO:0000256|RuleBase:RU365090};
KW Molybdenum {ECO:0000256|RuleBase:RU365090};
KW Molybdenum cofactor biosynthesis {ECO:0000256|ARBA:ARBA00023150,
KW ECO:0000256|RuleBase:RU365090};
KW Reference proteome {ECO:0000313|Proteomes:UP000031121};
KW Transferase {ECO:0000256|RuleBase:RU365090}.
FT DOMAIN 188..325
FT /note="MoaB/Mog"
FT /evidence="ECO:0000259|SMART:SM00852"
SQ SEQUENCE 418 AA; 43833 MW; 63F75C9858BF386B CRC64;
MPEMISLEEA RQLVLSKVRP LPIESVPLHD AVGRPAAANL ASDIDISPFA HSAMDGFALR
ADQIARASGE SPVELDVIAE VAAGDVFEGE IGEGQCVRIM TGAPLPEDAD CVVKYEVVGV
VSGEGKPGGR VSFSAPAKVR SNVREAGEEA RAGEVVVRVG EVVGSAGVGF LAGCGVTSVP
VHRRPRVAIV SIGSELVEAD QVPSRGKIRN SNAHALAACA SAAGAVAVRL PIVEDSLEAL
QAQIKRCASE YDFVVTSGGA SNGDFDFIKP AIQGAGELLM ATVNMRPGKA QAFGLVDGTP
VFGLPGNPAA AYLGFEMLIR PALRKMQGFS NFERPRVRAR LASDFKKKDP RRIFLRSTLT
KAEDGSYVVA PAKNQSSGLF GVIQRSNCFA IMPEGLESRE AGSLVECVLL DVSEDVAI
//
