ID A0A0A8LBG4_9SACH Unreviewed; 562 AA.
AC A0A0A8LBG4;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=glucan 1,4-alpha-glucosidase {ECO:0000256|ARBA:ARBA00012593};
DE EC=3.2.1.3 {ECO:0000256|ARBA:ARBA00012593};
DE AltName: Full=1,4-alpha-D-glucan glucohydrolase {ECO:0000256|ARBA:ARBA00033473};
DE AltName: Full=Glucan 1,4-alpha-glucosidase {ECO:0000256|ARBA:ARBA00033442};
GN ORFNames=KLDO_g3760 {ECO:0000313|EMBL:CDO95525.1};
OS Kluyveromyces dobzhanskii CBS 2104.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=1427455 {ECO:0000313|EMBL:CDO95525.1, ECO:0000313|Proteomes:UP000031516};
RN [1] {ECO:0000313|EMBL:CDO95525.1, ECO:0000313|Proteomes:UP000031516}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS2104 {ECO:0000313|Proteomes:UP000031516};
RA Nystedt B., Astrom S.;
RT "The genome of Kluyveromyces dobzhanskii.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues
CC successively from non-reducing ends of the chains with release of
CC beta-D-glucose.; EC=3.2.1.3;
CC Evidence={ECO:0000256|ARBA:ARBA00001863};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 15 family.
CC {ECO:0000256|ARBA:ARBA00006188}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDO95525.1}.
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DR EMBL; CCBQ010000045; CDO95525.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A8LBG4; -.
DR OrthoDB; 1586242at2759; -.
DR Proteomes; UP000031516; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004339; F:glucan 1,4-alpha-glucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 1.50.10.10; -; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR011613; GH15-like.
DR InterPro; IPR000165; Glucoamylase.
DR PANTHER; PTHR31616:SF11; GLUCOAMYLASE, INTRACELLULAR SPORULATION-SPECIFIC; 1.
DR PANTHER; PTHR31616; TREHALASE; 1.
DR Pfam; PF00723; Glyco_hydro_15; 1.
DR PRINTS; PR00736; GLHYDRLASE15.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023326};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 113..546
FT /note="GH15-like"
FT /evidence="ECO:0000259|Pfam:PF00723"
SQ SEQUENCE 562 AA; 64142 MW; 2FA574AA3D8FBC5E CRC64;
MLGTGSRKSK LPRNSHYVLS FICISSLLAY YFVFFPSHRD FNNAGQRLDR YLSDFSSFTE
VSDFSKTSAL KLQSISFSRN ISRNDFHGWL REQLDISLYH MFDNICEAET SSVFGNCTPG
VVFASPSRSE PDYFYHWIRD GAITINTLIN TNIDVDRERT LKTISNYINA SLDLQHKSNP
SGPADDPLFR NLGEPKYHVD NSPFEQVWGR PQNDGPPLRA IALLNFLTQL KDEVEREEFS
WIFDGVISLD LKFILQNWHI ATFDLWEEVC AYHFFTSMVQ LKALVEGRKH LLGVKASGIS
LSEANIVLLK DIESGIEKIE SFIKDANSGF IDHEKGYIVE TPSILDERSG LDIAVIMAST
LTHDELVNIS SSETFIFDVD DPLILNHFNE LIERMGVLYP INHNRLGTNM GVAIGRYPED
VYDGIDISEG NPWFISTLTS AELIFKLINK MYYDEKPLLV DPVKNKFLNR VFEFNRLSSS
PILIPYNTLA YNQTLYSIFK YGDSFLSKVN EHVTNEGSMS EQFNKYHGLN QGASDLTWSY
GTFCSALRWR GIVDRLLHPD TP
//
