ID   A0A0A8UP58_LEGHA        Unreviewed;       525 AA.
AC   A0A0A8UP58;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE            EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN   ORFNames=LHA_1491 {ECO:0000313|EMBL:CEK10533.1};
OS   Legionella hackeliae.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=449 {ECO:0000313|EMBL:CEK10533.1, ECO:0000313|Proteomes:UP000032803};
RN   [1] {ECO:0000313|Proteomes:UP000032803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC35250 {ECO:0000313|Proteomes:UP000032803};
RA   Gomez-Valero L.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC         (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC         diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LN681225; CEK10533.1; -; Genomic_DNA.
DR   RefSeq; WP_045105891.1; NZ_UGOC01000002.1.
DR   AlphaFoldDB; A0A0A8UP58; -.
DR   STRING; 449.LHA_1491; -.
DR   KEGG; lha:LHA_1491; -.
DR   PATRIC; fig|449.7.peg.707; -.
DR   HOGENOM; CLU_005138_6_2_6; -.
DR   OrthoDB; 9767858at2; -.
DR   Proteomes; UP000032803; Chromosome I.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR   Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR   PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR   PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   4: Predicted;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:CEK10533.1}.
FT   DOMAIN          308..432
FT                   /note="ATP-dependent DNA ligase family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50160"
SQ   SEQUENCE   525 AA;  60328 MW;  0BB010D6B98CA65C CRC64;
     MKTFSQLLNN LYFSYSHHAK LRLLQDFFAT TQDPERGYAI AILADTLEFP TFKRALIRGL
     IEKRIDPYLF ALSNDYVGDV SETLALAWPS STTMQSSLPS LTKVIHQLKK TPPNQMAASL
     AELLDNSNAI ERWALLKLGT GSLRVGVSAR FVKHALAKYG NVDIKDIEHV WHALEPPYVE
     LFAWLEGKQA APEISNAVFF HPVMLSHPLK EKDLPLITED TFFAEHKYDG IRVQFVSSTQ
     EKALYSRTGD NISVSFPDVV SEINTPVVLD GELVVLNQTN IGSFNDLQQR LNRKKLSDKI
     LKEQPAAIIL YDILKMETDD LRTLPLYERR QLLEAWYARH RPKNMWLSEL LSFSNLNGLL
     ELKETVLAKQ HVAVEGLMLK RKDSPYIAGR PVGHWYKWKR DPHLIDAVLM YAQRGHGKRS
     SFYSDYTFGL WQNDKLLPVG KAYFGFTDEE LYQLDKWIRY HTQHRFGPVR EVEKTLVFEV
     AFDAVNFSSR HKSGVALRFP RIHRIRWDKP ANEADSLDTL VALIK
//