ID   A0A0A8UTH0_LEGHA        Unreviewed;       437 AA.
AC   A0A0A8UTH0;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=L-lysine 6-monooxygenase (NADPH) {ECO:0000313|EMBL:CEK10397.1};
DE            EC=1.14.13.59 {ECO:0000313|EMBL:CEK10397.1};
GN   Name=iucD {ECO:0000313|EMBL:CEK10397.1};
GN   ORFNames=LHA_1351 {ECO:0000313|EMBL:CEK10397.1};
OS   Legionella hackeliae.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=449 {ECO:0000313|EMBL:CEK10397.1, ECO:0000313|Proteomes:UP000032803};
RN   [1] {ECO:0000313|Proteomes:UP000032803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC35250 {ECO:0000313|Proteomes:UP000032803};
RA   Gomez-Valero L.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
CC   -!- SIMILARITY: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-
CC       oxygenase family. {ECO:0000256|ARBA:ARBA00007588}.
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DR   EMBL; LN681225; CEK10397.1; -; Genomic_DNA.
DR   RefSeq; WP_045105779.1; NZ_UGOC01000002.1.
DR   AlphaFoldDB; A0A0A8UTH0; -.
DR   STRING; 449.LHA_1351; -.
DR   KEGG; lha:LHA_1351; -.
DR   PATRIC; fig|449.7.peg.520; -.
DR   HOGENOM; CLU_020931_0_0_6; -.
DR   OrthoDB; 7527071at2; -.
DR   Proteomes; UP000032803; Chromosome I.
DR   GO; GO:0047091; F:L-lysine 6-monooxygenase (NADPH) activity; IEA:UniProtKB-EC.
DR   GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR   GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR025700; Lys/Orn_oxygenase.
DR   PANTHER; PTHR42802:SF1; L-ORNITHINE N(5)-MONOOXYGENASE; 1.
DR   PANTHER; PTHR42802; MONOOXYGENASE; 1.
DR   Pfam; PF13434; Lys_Orn_oxgnase; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE   3: Inferred from homology;
KW   Monooxygenase {ECO:0000313|EMBL:CEK10397.1};
KW   Oxidoreductase {ECO:0000313|EMBL:CEK10397.1}.
SQ   SEQUENCE   437 AA;  50430 MW;  98F9E2F7A2DA0F4E CRC64;
     MLYHLAEDVF DLLGVGIGPF NLSLAALLTP TKEIKSSFFD QNKSFIWHPG MLLPDAELQV
     SFLYDLVTLV DPTNPYSFIS YLAKNKRLYR FLNAQFKQVP RGEFSEYLSW VSRSLPNLFF
     EEKIEDITFN NSLFTITTTQ RKTYSRNLVL GSGLKAKIPS CGQNLLGQDV FHSKDFLLNL
     KHWHGKKIVV LGGGQSGAEI VHYLLSHSSQ FPEKLFWITK RNQFSALDDS TFSNEFFTPQ
     YADYFFSLDE KQKAIRLHQQ ILASDGISLP LLDKIYQKLY KLEFIEDKGH FFRLIINHQL
     IKLARESNHY HLVLSECEGN NKQIINADIV IFCTGYEWEF PDYLSSLANR IPLKNGQFYM
     HSDFSIQWDG PKKNRIYAQN ASRQQYGIAE PNLTLMAWRS AKIINSLCNA PIYQLDAENT
     ALDLQTQGGF KYALNEW
//