ID A0A0B1P4A2_UNCNE Unreviewed; 1053 AA.
AC A0A0B1P4A2;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=GPI ethanolamine phosphate transferase 3 {ECO:0000256|ARBA:ARBA00020841};
GN ORFNames=EV44_g5408 {ECO:0000313|EMBL:KHJ32160.1};
OS Uncinula necator (Grape powdery mildew).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Erysiphe.
OX NCBI_TaxID=52586 {ECO:0000313|EMBL:KHJ32160.1, ECO:0000313|Proteomes:UP000030854};
RN [1] {ECO:0000313|EMBL:KHJ32160.1, ECO:0000313|Proteomes:UP000030854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=c {ECO:0000313|Proteomes:UP000030854};
RX PubMed=25487071;
RA Jones L., Riaz S., Morales-Cruz A., Amrine K.C., McGuire B., Gubler W.D.,
RA Walker M.A., Cantu D.;
RT "Adaptive genomic structural variation in the grape powdery mildew
RT pathogen, Erysiphe necator.";
RL BMC Genomics 15:1081-1081(2014).
CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
CC {ECO:0000256|ARBA:ARBA00008695}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHJ32160.1}.
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DR EMBL; JNVN01002280; KHJ32160.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B1P4A2; -.
DR STRING; 52586.A0A0B1P4A2; -.
DR HOGENOM; CLU_004298_1_0_1; -.
DR OMA; YPSFDIF; -.
DR OrthoDB; 5479199at2759; -.
DR UniPathway; UPA00196; -.
DR Proteomes; UP000030854; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051377; F:mannose-ethanolamine phosphotransferase activity; IEA:InterPro.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd16023; GPI_EPT_3; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR002591; Phosphodiest/P_Trfase.
DR InterPro; IPR037675; PIG-O_N.
DR InterPro; IPR039524; PIGO/GPI13.
DR PANTHER; PTHR23071:SF1; GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3; 1.
DR PANTHER; PTHR23071; PHOSPHATIDYLINOSITOL GLYCAN; 1.
DR Pfam; PF01663; Phosphodiest; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030854};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KHJ32160.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 50..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 491..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 556..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 581..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 621..639
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 645..661
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 673..691
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 716..734
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 746..769
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 851..878
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 941..965
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 977..1002
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1017..1039
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1053 AA; 118484 MW; 7905372620FE2515 CRC64;
MSSQNLQTIE NTRLDPLGKI NGLNTSENRK NVIHKLNETK KENFIREWHW GLAFFIWLLL
IHIIGVYFFT KGFLLTRLVL KEKSSCEAQV NISIEPFKGK STYDAGCWHP KSFDKAVIIV
IDALRYDFTI PYTGNHKKFF HNELPILYNT TIMEPHSSFL LPFIADPPTT TLQRLKGLTT
GTLPTLIDLG SSFSGTAIEE DNLLIQLKDA GKRIVHLGDD TWTKLFPKYF EENISKAYDS
FNVWDLHTVD NGVTENLKPL LRRDKKETWD IIIAHYLGVD HAGHRYGPDH PAMASKLQQM
NNVLIDIVST IDKDTLLVVM GDHGMDLKGD HGGESDDEVQ SALWMFSRKE IFGRTDPKHF
IPPLSAKERF VNQIDIVPTL ALLLGIPIPF NNLGKPIQEA FVGKKGNDWK NLASVARITA
AGTKKYKSTY HATRGFTKPA DTDSVENIWV SGEKIPINSG KKSAKEAFLT FSAFSDETLK
MCRNLWAQYD LPSMIFGIGI LTLSIILLIS YAYEILQEEP QTNDSEVDQV QFQLELQNFS
KGIKTNHSDK SPSKRIFGNI LNYSLLGVIF SPIFWNFTRT FSVIDIGLST FATSGLLGVL
YQEFFRKVAF DKIFTKNYWS WLAFTFTISQ ALGFASNSYT IWEDSILLFF LSTFGISAMI
SSSRIRKSSD RALGIYHSLI FTILSWVASF SKLCREEQMP YCQTTYYISS TSSTSALWQV
VIPFIVALIL PSIIKSFYTG SRSYEGFAPI WIGWVFRIGL TLNAIFWTID AADDGQWFPS
ITSTFLKKTR VVIAQTILSS VIGAGSTAFV YAPPCVSVTT TMDSKSGHQG SNSPNPKITI
LGFANVHGTR YFLLLLNVIL GIFLLQKPMG AGALSLMAWQ ILALSEILDL NSLASSPIGP
IMLALLGSFH FFKTGHQATL SSIQWESAFI PFHSIYYPYS AILVALNTFG AQVFAVAAVP
LLVLWKQKPR KKNIFRSVLR ALAWHICYYA IMAASTSLWA AWLRRHLMLY RIFSPKYMTA
VSVLFMVDIF GILVVLIGFR SNISSISEIF GWS
//
