ID A0A0B1SRY0_OESDE Unreviewed; 208 AA.
AC A0A0B1SRY0;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Putative 4-hydroxyphenylpyruvate dioxygenase {ECO:0000313|EMBL:KHJ87689.1};
GN ORFNames=OESDEN_12530 {ECO:0000313|EMBL:KHJ87689.1};
OS Oesophagostomum dentatum (Nodular worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Strongylidae; Oesophagostomum.
OX NCBI_TaxID=61180 {ECO:0000313|EMBL:KHJ87689.1, ECO:0000313|Proteomes:UP000053660};
RN [1] {ECO:0000313|EMBL:KHJ87689.1, ECO:0000313|Proteomes:UP000053660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OD-Hann {ECO:0000313|EMBL:KHJ87689.1,
RC ECO:0000313|Proteomes:UP000053660};
RA Mitreva M.;
RT "Draft genome of the hookworm Oesophagostomum dentatum.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|ARBA:ARBA00001962};
CC -!- SIMILARITY: Belongs to the 4HPPD family.
CC {ECO:0000256|ARBA:ARBA00005877}.
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DR EMBL; KN557247; KHJ87689.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B1SRY0; -.
DR Proteomes; UP000053660; Unassembled WGS sequence.
DR GO; GO:0003868; F:4-hydroxyphenylpyruvate dioxygenase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009072; P:aromatic amino acid metabolic process; IEA:InterPro.
DR CDD; cd07250; HPPD_C_like; 1.
DR Gene3D; 3.10.180.10; 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1; 1.
DR InterPro; IPR005956; 4OHPhenylPyrv_dOase.
DR InterPro; IPR041735; 4OHPhenylPyrv_dOase_C.
DR InterPro; IPR029068; Glyas_Bleomycin-R_OHBP_Dase.
DR InterPro; IPR004360; Glyas_Fos-R_dOase_dom.
DR InterPro; IPR037523; VOC.
DR PANTHER; PTHR11959; 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE; 1.
DR PANTHER; PTHR11959:SF3; PROTEIN C31H2.4-RELATED; 1.
DR Pfam; PF00903; Glyoxalase; 1.
DR SUPFAM; SSF54593; Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase; 1.
DR PROSITE; PS51819; VOC; 1.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000313|EMBL:KHJ87689.1};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:KHJ87689.1};
KW Pyruvate {ECO:0000313|EMBL:KHJ87689.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053660};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 2..161
FT /note="VOC"
FT /evidence="ECO:0000259|PROSITE:PS51819"
SQ SEQUENCE 208 AA; 24162 MW; C5A4A9CEAF583F8E CRC64;
MLLDHVVQNY PINTIEDTAE WYRETMALQR FWSIDDKITT SEYSAMKAWL ITSDDQKVQM
TLAEAVPGRK GISQIEEFVA YNGGPGIQHI ALRVDDIVAT VTEMRKRSIE FLHVPSSYYD
ILEDRLKNSK VELKEDIAKL RELCILMDFD DNGYLLQLFT KPVQDRPTLF IEIIQRRNFN
GFGAGNFKAL FDAVEREQRL RGTLYDEN
//
