ID A0A0B1ZI43_9SPHN Unreviewed; 358 AA.
AC A0A0B1ZI43;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:KHK90152.1};
GN ORFNames=LK12_15845 {ECO:0000313|EMBL:KHK90152.1};
OS Novosphingobium malaysiense.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=1348853 {ECO:0000313|EMBL:KHK90152.1, ECO:0000313|Proteomes:UP000031057};
RN [1] {ECO:0000313|EMBL:KHK90152.1, ECO:0000313|Proteomes:UP000031057}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUSC 273 {ECO:0000313|EMBL:KHK90152.1,
RC ECO:0000313|Proteomes:UP000031057};
RA Lee L.-H.;
RT "Genome sequence of Novosphingobium malaysiense MUSC 273(T).";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHK90152.1}.
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DR EMBL; JTDI01000005; KHK90152.1; -; Genomic_DNA.
DR RefSeq; WP_039286218.1; NZ_JTDI01000005.1.
DR AlphaFoldDB; A0A0B1ZI43; -.
DR STRING; 1348853.LK12_15845; -.
DR OrthoDB; 9770544at2; -.
DR Proteomes; UP000031057; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08279; Zn_ADH_class_III; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43880; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR43880:SF12; ALCOHOL DEHYDROGENASE CLASS-3; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000031057};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 7..356
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
FT REGION 97..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 358 AA; 37171 MW; 6C264238FE67F1CB CRC64;
MKAAVLRQIG QLDIEDVDLD GPRRDEVRIR VLASGLCHSD YHFIAGDFPV PLPAVLGHEV
AGEIIAVGEN VGGFAIGDRV VTCLSAYCGQ CRECQTGHNH RCEDKPGAPD RPAGSRITKG
GEAIRQLGNL GGFAEEMVIH HRAVTKISPE VPPSSAALLG CAVITGVGSV LNSAKVPPGS
TVAVIGCGGV GLNAIQGARI AGASRIIAVD KNAAKLSAAI AFGATDTVLG GPDTAGEIAE
LTRGGVDFAF EVVGSEATAR LAMDATRQGG TTVLVGLGTP DLTVALPITT FAMTEKRVMG
SLMGSAAYQL FLPQLVTYYQ QGRLKLNELV SREIRLDQIN EGYASMANGE VARSVIVF
//
