ID A0A0B2VEK3_TOXCA Unreviewed; 731 AA.
AC A0A0B2VEK3;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=E3 ubiquitin-protein ligase TRIM33 {ECO:0000313|EMBL:KHN79440.1};
GN Name=trim33 {ECO:0000313|EMBL:KHN79440.1};
GN ORFNames=Tcan_08227 {ECO:0000313|EMBL:KHN79440.1};
OS Toxocara canis (Canine roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN79440.1, ECO:0000313|Proteomes:UP000031036};
RN [1] {ECO:0000313|EMBL:KHN79440.1, ECO:0000313|Proteomes:UP000031036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN79440.1};
RA Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA Gasser R.B.;
RT "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN79440.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JPKZ01001919; KHN79440.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2VEK3; -.
DR STRING; 6265.A0A0B2VEK3; -.
DR Proteomes; UP000031036; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15541; PHD_TIF1_like; 2.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45915:SF6; FINGER PROTEIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR45915; TRANSCRIPTION INTERMEDIARY FACTOR; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 2.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS50014; BROMODOMAIN_2; 2.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 283..338
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 365..437
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 502..557
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 584..656
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 165..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 252..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 713..731
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 731 AA; 81302 MW; 738E0672DBDFBE64 CRC64;
MAMRQPQAQP SAQSVNNTPP TNDPRYAAAL RQQMRAPSMH PNVAYRFPPA PYCYRGAAAH
NSSFDPRFAA GQQYMLPNAP PPVSYPAPQM APPNIPLSSI SSPIPATNLM EALATNQPFS
TCVTSNSSGV VQPNEPAVAT REMPPNIAHG AAPDEERKKI ISQEMEEARR RREAAQLGER
ISQTETPTSS ADCSARSGSA QPSEITSTTQ GSSVDQSSSQ VTSSTSNSSP PPKDPAPLRS
LKVTIRRCST GGATTSLVND PEHVASTTVS NTNGENADES KWDDYCYVCQ QGCDEKTGSL
GCCARCPHVY HNYCHVPPIK QPMESLPDEW ACSLCMPAEP LHEDSGVMGS RERLLCSKVL
LRCYEHFLQA EPFSHPVPKT VPNYYVIIKH PMDFGTIARR LRERAKDAFV SVLQFIQCMN
LVFENCSTFN PGLNAKFSLA MWLHGFVDFM SFLPIGWPVS NTNGENADES KWDDYCYVCQ
QGCDEKTVSN TNGENADESK WDDYCYVCQQ GCDEKTGSLG CCARCPHVYH NYCHVPPIKQ
PMESLPDEWA CSLCMPAEPL HEDSGVMGSR ERLLCSKVLL RCYEHFLQAE PFSHPVPKTV
PNYYVIIKHP MDFGTIARRL RERAKDAFVS VLQFIQCMNL VFENCSTFNP PDDEVAQAGR
SVYNLYSKAV KEFLPCMKGF VWLYINKYSE GRNNMIVQKD SGLQQVRPRS SESSSEPHAK
KPRKEIKDEI D
//
