ID   A0A0B2VG12_TOXCA        Unreviewed;       756 AA.
AC   A0A0B2VG12;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Putative RNA-binding protein orb2 {ECO:0000313|EMBL:KHN80322.1};
GN   Name=orb2 {ECO:0000313|EMBL:KHN80322.1};
GN   ORFNames=Tcan_06495 {ECO:0000313|EMBL:KHN80322.1};
OS   Toxocara canis (Canine roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX   NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN80322.1, ECO:0000313|Proteomes:UP000031036};
RN   [1] {ECO:0000313|EMBL:KHN80322.1, ECO:0000313|Proteomes:UP000031036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN80322.1};
RA   Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA   von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA   Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA   Gasser R.B.;
RT   "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN80322.1}.
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DR   EMBL; JPKZ01001748; KHN80322.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B2VG12; -.
DR   STRING; 6265.A0A0B2VG12; -.
DR   Proteomes; UP000031036; Unassembled WGS sequence.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:InterPro.
DR   GO; GO:0045182; F:translation regulator activity; IEA:InterPro.
DR   CDD; cd19757; Bbox1; 1.
DR   CDD; cd12724; RRM1_CPEB2_like; 1.
DR   CDD; cd12726; RRM2_CPEB2_like; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   Gene3D; 4.10.640.40; Cytoplasmic polyadenylation element-binding protein, ZZ domain; 1.
DR   InterPro; IPR032296; CEBP_ZZ.
DR   InterPro; IPR038446; CEBP_ZZ_sf.
DR   InterPro; IPR034819; CPEB.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   PANTHER; PTHR12566; CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB; 1.
DR   PANTHER; PTHR12566:SF12; TRANSLATIONAL REGULATOR ORB2; 1.
DR   Pfam; PF16366; CEBP_ZZ; 1.
DR   Pfam; PF16367; RRM_7; 1.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR   PROSITE; PS50102; RRM; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00176}.
FT   DOMAIN          619..697
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   REGION          1..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          66..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          185..206
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          257..331
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          363..385
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..34
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        85..99
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        288..331
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        367..385
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   756 AA;  84096 MW;  8811D3AC2A9A4042 CRC64;
     MSGVPGIRGV CNSAAGRVTE DHGDESKEVP NESDSKLVHT ALELAWSLFG PNTTVVKTLQ
     MAPGCMHTDS ERHSTPSSES GTVTDEDMTS KEISNDSHYK RSASDGALFV RSTNTYETVP
     NRVISSAVGM NIPTENNVVT SGILNDFRGE KLGGNANKFT RPKSPVSFDI PRPHGAHAQL
     KTANTMSKSL TDETRNAEGD KDNKETLRQR HRELVEEYFQ HCADFRHPKL QFGHRDQTWQ
     DRYYYEYHQY LCKLSSNSNS TSMSSEDHRG PPGSICLNGF EGERSGASSG RRSARRNRRD
     QNTSHEERDE LNDSRNGEHG DESKEVPNES DSKLVHTALE LAWSLFGPNT TVVKTLQMAP
     GCMHTDSERH STPSSGHSTS TRSSSRAIKS DLYYQYNPGS EIYSRKVFAG GLPIDIDEES
     GTVTDEDMTS KEISNDSHYK RSASDGALFV RSTNTYETVP NRVISSAVGM NIPTENNVVT
     SGILNDFRGE KLGGNANKFT RPKSPVSFDI PRPHGAHAQL KTANNELSAT FSSFGPLVVD
     WPNKNENNSY FPPKGYVFLI FEYEVSVRAL VQSCFVEDEK LFLYISSPLS PDKLVQIRPW
     RLADADYVVD PNISISAHRA VFVGGVPRPI KAVELAHIMD RLYGSVACAG IDTDVEYKYP
     KGAGRVVFTN RNSYMKAIAD RYVQLSHGEV EKTVEIKPYV LDDQPCDECG GERCAHRPAP
     FFCPHLSCLQ YYCEKCWESI HASRAREDHK PLVKEA
//