ID A0A0B2VJK9_TOXCA Unreviewed; 3999 AA.
AC A0A0B2VJK9;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Phosphatidylinositol phosphatase PTPRQ {ECO:0000313|EMBL:KHN81205.1};
GN Name=PTPRQ {ECO:0000313|EMBL:KHN81205.1};
GN ORFNames=Tcan_15324 {ECO:0000313|EMBL:KHN81205.1};
OS Toxocara canis (Canine roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN81205.1, ECO:0000313|Proteomes:UP000031036};
RN [1] {ECO:0000313|EMBL:KHN81205.1, ECO:0000313|Proteomes:UP000031036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN81205.1};
RA Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA Gasser R.B.;
RT "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN81205.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JPKZ01001575; KHN81205.1; -; Genomic_DNA.
DR STRING; 6265.A0A0B2VJK9; -.
DR OMA; QYSTYHI; -.
DR Proteomes; UP000031036; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 27.
DR Gene3D; 2.60.40.10; Immunoglobulins; 31.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR46957; CYTOKINE RECEPTOR; 1.
DR PANTHER; PTHR46957:SF3; PROTEIN-TYROSINE-PHOSPHATASE; 1.
DR Pfam; PF00041; fn3; 18.
DR SMART; SM00060; FN3; 34.
DR SUPFAM; SSF49265; Fibronectin type III; 20.
DR PROSITE; PS50853; FN3; 27.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..3999
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002096186"
FT TRANSMEM 3975..3998
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 139..230
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 231..327
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 436..530
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 681..769
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1035..1134
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1136..1227
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1335..1426
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1430..1529
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1530..1625
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1740..1835
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1840..1938
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1940..2032
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2036..2138
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2142..2237
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2242..2346
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2350..2448
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2495..2587
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2591..2687
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2692..2785
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2787..2893
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2898..3001
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3004..3103
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3213..3307
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3311..3420
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3425..3521
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3528..3629
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3630..3723
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 540..563
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1918..1947
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2124..2143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2474..2503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2670..2698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3999 AA; 449580 MW; 577E7AF1FDD496B9 CRC64;
MGAVSAGLRA LLILLFISLI KGSRPDARVR RDTGGSQSLL TVEWEGIQTG DHPDDTVGGF
AVEYRAEKDT QWHVHDGIIP YKGPNLQYRV QIPRLPTGIA YFVRIKVLGK NGKILVETPE
IRARNEMVSI KCESDDLTAP RNVEITQTGQ YSVAISWEPP ECGSVGEYHI ELSGIETQFD
VHRQTVTHPS VSVTNLLPGT EYQVRVRAAD RSRNLGPWNE HTTVARTQGH APESSSEVET
DYRTDTQLRI HWPHYEDERL QFYEVMAVEV NSEGRSVERV RVAPIINSHA FGGLRPGTEY
LIGVVAFVDH EPHYVYKHST KTTTSPGVEW EEKPTVVKEG AQHFIVRWNK PDMKQPISNF
IVEYRLPNET EWRKYGDVPV DEDSNDYQMV VETIGDTTFY SLRVMVVDDQ QILLAKTPEV
TVGSTSVESC AGDAGIPQDV RVAFVSESTL QYTWEKPHCD ESYGPIDGYE YASWNVETGT
QPEGASYVGR NAVALNDLEP DSRYAFRVRS RSGHGHSPWS DVVHASTKAH SGVIAIGGRV
SLTSPNETSG TPHRREKRQD KNKITDDRNI YQLRIVLAPP RSYLVWTPLQ EHIKEVAKFK
LSYKKSASDE WTRVVQSPSF FICPEGIADE EDYCYDLAQF SYGVQYTADL VYQLHSGEWS
SHGTPLFFIL VEAGEPSIPS APNNLQISPR DASSVELRWL PPLSSIIIED MHSGDVRTEK
VPGSYFAHIV SQLSPYSTYN ISVRGATDLG DFGLAASDVV SLQHYTGHHQ EIPQSETPPI
RCEPTAPSAP CFPPSRARPS LGIEQPRIEQ RGSRIILYWD VGGDTSNVVA YQIDLRSETD
RDWSQYGDHI THIPSERQFR QELEHLRTNG RYFVRVLAHD RSRHPIAISP VASFTVHCQV
PSAAPQDVRL EDVPDGVLLK WTFSNHESSE CMPYFLITGY QNGIPFNQKV DGRVREYRFE
NPVGGEWQAE LRAGNTAGTG PASSIVKLQT EHQVNTVNVR VRVHRSICDP RTDFWCRAPG
QSSEYSTSRQ LDEALISAPR VMARGGDLNV EWDSEGNGRG VFGYRVQFRS DSTGWNPYGQ
IVPYVGDNQR YSQLLTGLQL GKNYYVHIQV LDRNSYVMYT SPEVSARTIC TAPSHPPSHL
QIEAPDSRHV RVSWVTPPQS TWQCNNIQVE LQAIEPTGET PVLLGGRQTT HVFASDANQP
WTVQIRSKNT AGYSPWSASV STRTPPAGEL IIGPNINYRQ GIPIISWSSK ERVDDLVDAY
QIEWKSLRQG HWQKYRAQIP FSGWQRPYSV DLSELPAGET YQVRVNVIDP NRAIAYTSPT
VNIQTQPRCS SPRRPPSDVI VSPIGPTQIR LSWRTLHETE WNCDRIWYVV KYSTPRNQGF
RNLTSGENEV IFDSEPFTQW TFEVQAANPG GESQWSRPVV TQTQGTAPGP VSDFRIYPMS
PDSLQLSWRQ PQNPNGQITG YEITYQLLSK GMCDQTPERA ITVSSERPSY TLQGLSPHSR
YRISVAAKTN IAGEPVTEEV QTDQATPSAA PLYIRADNPL PTEVDVTWQA PPCLQTNGEI
TEYEYELRHV DGDSQVPFKT NTVRGTRARI VDLNPFTRYT IRLRSYTRKG PGPWSEPVHF
QTAAAPQMEP PPMVRVIDTG PDTAHLVWQQ PRGYVDKYKC QYAIVGTETY QERVFPANNP
CALDVRIERL PSVPQGSRLH CGRIDGLQPE REYDFKISAG GPGGQWSPWS ESQRGHITEG
PVHISSISRL GSTANSLHIG WVVKPADAAR IGGFRIYVTP LGRGARPQTF SVDRSTTQYH
VDNLSPNTLY NITVQATTGS KSHPGTSVEM RTDIAPLRGL LSAPRVIEEQ PTSVKLEWDA
PPGEYSGFIV EFRLGDGAWQ QYSRRVPAYP GRRTYVSQID QLPTNNAVDL RVRVVSMQNE
QSPPSAEVRA RTKCTAPSAP PQGIRVDAPS TNEVRISWAR PAKDTWQCDQ LSFDIAYRVG
NQPERIVPVP GDQTEYVFPA EPNTRWAIKL RSSNQVGSSP WSSEQTITTR QGTPGAVRDL
RLRAKGPNEV HVQWLPPLVQ RGTIVGYDIS YRLKHRLACP SEEPRDVSRD FITVYNHKDL
EYTLTGLLPF SLYEVRVRAR TTELGPEETK EIATEQQPPS APPLNLQTGY ALERSINFQW
EPVECSQRHG HITSYEYEIL GQDDWAKLER QIANTTDNKI TIDGLTPFTK YVMRVKAFNS
IGGGPNTENL DAMTAKADAP LPPQDLVVAL EGTDFFMVSW LPPYPPYGPH DVYRLRYQLL
NAKTWNSIEK NIKDPALQCP AESPRYCYNV TGLENGQQYR VQVATHIEGG SYGPWSSPII
ANTLQVLPDA PRAIELIDKT DHSLHIRWLP PPDPMGHITQ YKVSIVSMED PRDEVKSFLV
DHPTLTYLLG NLQPETSYNV SISAGTKRGF GPIIWTRYST DPFKVPSITN APQLANLDAD
TLYFVRIKAV DKKQRVSQPS PEGRGRTGCA APRSPPLNVN AQSPSSRQVR VSWLAPVQSS
WLCSNIRYKI EYYNGSAPRQ QVDLPSGITE HVLDSAPNTI WRVRVRVEND AGASEWSKEV
SVTTAEGAPG AVSDLDARPT GPNSAAVTWR PPAQTNGIIT GYTVVYQLKS RGECGPRSSQ
PITKHVHGDR LVLDDLLPDS TYEVHVVAHT SQAGPQSETV TVTTDEAPPT GAPQNVHMSS
VTQTRADLLW NEPDCELRNG KIVDYDYELQ SLDDWDENRT DHSSVRRVSF DRLVPYTRYR
ARVRANNAKG EGPFSEWIAF QTLPASPPQP TDLVEERSFP HAIEISFLPP SPPHGNINEY
RIRQTPAGQL NYKEVRMPAH RLECSDASKR ERLCYRVVDL DPEQEYEIQV AGHTDGGGWG
EWSDPLSART HEQNIPVLER ELQVVDTKPT SITVKWQGLD QNQAAHVVGY VLEYKSENED
DDWQEYNGIT KHRSRQNEYK VQVRGLEEAT EYFFRLKVIG KNDKRGAPGP EVKAVTNCGR
PEEPPGHVKL ESIDFETIKL SWKNPEEVSW KCDEVEYVID FVNTTSRGVL TVPFDSPEEL
ILPTVPGTKW EIKMRTQTVE EGQKPQYSPW SERASLITQA LPGELFVKVE SKSPKSAVVI
WDLADQDQKW NYGVDITYKL KQLGGCLEAQ SGDHEPITKY NVQDKQIVLD DLKPGSEYEV
IVTPRKPPTL HSSIETPKTV RRFRTETDVP SGPPVNLRSD SRKDTEIGFK WEAPPCENQN
GKITQYEYQV SGVDEWNEGQ REGVTPRTNA VVDQLKPGSL YNVRVRAYTK EGEGPWSQTI
QIRTTGSELG APRELTAVQT KPKSIQLTWL PPYPERAPVV AYKIKHSPRA DDSNPVEVEL
SGNELSCAGY KSPLITSDNL CATAVGLQPD TTYRFAVQAQ STSGNWGDWS PSYFATTRST
DDGPIPGKLR LVSAGHDNLR VNWTVPPVIR DLIDLYLVNI SVASALDQHP HEYRTPGSQT
DYHFHGLDPV THYNITVQGL SKGKRLWFIS EVFATTDFAE GLLLWLPSPT DLKLLEKSDT
MMHVAWSPPE IFDPQYKDLI THYRVTIAPF DAVRGVTGRP KNYTVPYPGS SIRFEDLRPD
TIYNITVQAG TDSGYGQILW GTYSTLAPGQ NHILRLVYRT PTTLTVEWEP VWATDRGYIL
IWKSLHSAYP HTRLNVIRST QIDGSATNFT IRDLEPSTVY NVTLQPRGIS DGAYGVYATL
PPGWFVVRNL VYCDKTNYAI SLNWEPVDLN MATHYQVRYL RLKEHDAVWN EEPAQRAVEL
LCPKDGCNRH CYLVYNLDFN PSEYVFQVRA KVNDQWNHWK TAGKPSVSEK ADRRKGCCIV
PPPYMVEHIG APGTFWEVDV GPVESQPQNI SRYYVVVDER EPAGNTNWTE LTDKVTATKH
KLPYYVAASF NADTLLSPRK VRIGDGSVIG GYLNYPLIKG KKYNYEIYSL WELDGKQAVV
ARQREVKGWW AAVPWYYLLL VALPLLLLSC CLAGLCYYL
//
