ID A0A0B2VTB4_TOXCA Unreviewed; 655 AA.
AC A0A0B2VTB4;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Tyrosine-protein phosphatase non-receptor type 9 {ECO:0000313|EMBL:KHN84604.1};
GN Name=PTPN9 {ECO:0000313|EMBL:KHN84604.1};
GN ORFNames=Tcan_09214 {ECO:0000313|EMBL:KHN84604.1};
OS Toxocara canis (Canine roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN84604.1, ECO:0000313|Proteomes:UP000031036};
RN [1] {ECO:0000313|EMBL:KHN84604.1, ECO:0000313|Proteomes:UP000031036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN84604.1};
RA Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA Gasser R.B.;
RT "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN84604.1}.
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DR EMBL; JPKZ01000912; KHN84604.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2VTB4; -.
DR STRING; 6265.A0A0B2VTB4; -.
DR Proteomes; UP000031036; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0042302; F:structural constituent of cuticle; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd00047; PTPc; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR002486; Col_cuticle_N.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR46163; TYROSINE-PROTEIN PHOSPHATASE-RELATED; 1.
DR Pfam; PF01484; Col_cuticle_N; 1.
DR Pfam; PF01391; Collagen; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM01088; Col_cuticle_N; 1.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:KHN84604.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 368..625
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 548..616
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 108..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 153..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..260
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 655 AA; 70558 MW; D6A88F07F1CDF663 CRC64;
MQARALVLAA SIGCVIVLSA SIIVVGILFD DLNKLYYEVL DDMREFKILT SDAWEEIMSV
HALKDGAIIG EDRSAFTGIV MRDKRRAVRE RKNVICACAP PPPYCRPGPR GPPGDAGLPG
VPGLNGTNGR PGLDGIQISY GINTAGGCIM CPAGPPGERG PPGKQGLPGP DGMVGKPGGI
GFPVKRGPRG PPGPPGDQGI PGRTGVPGRR GPSGASGIGG KALRGPKGPA GKHGLPGPAG
PPGSSGRPGL PGPPGLRGPP GHSGMPGKRG RPGPPGERGM PGNDARYCPC PPRSSYVAQR
SRGVQTRPLL SKNAKRDGTT EETIFTMETV EEEEIRNDKQ SKLKKKPSSV LAFEKFAIDT
VAKKIEGLQA EFAALKSFTP INTAQTAFMA HKDRNRYSNI PCFDTTRVVL TYGVPPETDY
IHANYVKTAM CNLRNTYICT QAPMESTIND FWRMVWQEKP KCIVMLCKLF EGGKSKCAQY
FPAKASETQQ YGSVVVQNIK KTSPVNETVF ESIQLNVCVA GQPTIAVTLF KWLDWPDFGV
PSSGMGMLRI LRQIRDQPHT KAIIHCSAGV GRTGTMIACE ICLRTLLEGK ELNVIDVVKE
IRSQRACAIQ TEGQYVYLHR TLLEYINAKK IAKERNAEFF AAYKTYQKRS EKVAA
//
