ID A0A0B3S581_9RHOB Unreviewed; 320 AA.
AC A0A0B3S581;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=D-3-phosphoglycerate dehydrogenase {ECO:0000313|EMBL:KHQ51841.1};
DE EC=1.1.1.95 {ECO:0000313|EMBL:KHQ51841.1};
GN ORFNames=OA50_03478 {ECO:0000313|EMBL:KHQ51841.1};
OS Mameliella alba.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Mameliella.
OX NCBI_TaxID=561184 {ECO:0000313|EMBL:KHQ51841.1, ECO:0000313|Proteomes:UP000030960};
RN [1] {ECO:0000313|EMBL:KHQ51841.1, ECO:0000313|Proteomes:UP000030960}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UMTAT08 {ECO:0000313|EMBL:KHQ51841.1,
RC ECO:0000313|Proteomes:UP000030960};
RA Gan H.Y., Muhd D.-D., Mohd Noor M.E., Yeong Y.S., Usup G.;
RT "Genome sequence of Ponticoccus sp. strain UMTAT08 isolated from clonal
RT culture of toxic dinoflagellate Alexandrium tamiyavanichii.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHQ51841.1}.
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DR EMBL; JSUQ01000014; KHQ51841.1; -; Genomic_DNA.
DR RefSeq; WP_043143964.1; NZ_JSUQ01000014.1.
DR AlphaFoldDB; A0A0B3S581; -.
DR STRING; 561184.SAMN05216376_104350; -.
DR PATRIC; fig|1515334.3.peg.3494; -.
DR OrthoDB; 9793626at2; -.
DR Proteomes; UP000030960; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:UniProtKB-EC.
DR CDD; cd12156; HPPR; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719,
KW ECO:0000313|EMBL:KHQ51841.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000030960}.
FT DOMAIN 6..312
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 109..281
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 320 AA; 34122 MW; E8EC044064D70FDA CRC64;
MSKEDVLVLY PARPKAMEQL EAAYTLHRLD EAEDKAGFLA EHGPRCRGIV TNGHAALTRA
DLEHLPNLEI VCCSSAGFES IDDAALREKG IALTNSSDAL CDDVADTAVM LTLACRRDLV
AAHDYVKSGD WGRKGMYPLL SALKGKKVGI AGLGTIGKAI ASRLTPFRVC LGYHSRRPKP
VDHAYFETVT ELARWADILI VIVPGGPETE GMINAEVLEA LGPQGTLINV ARGSVVNEAD
LIAALTSGTL GNAGLDVYLN EPNPDPALTA LPNVTLYPHH ASGTVETRDA MAQTVVDNLR
AHFAGEPLLN PVYTLPESVA
//
