ID A0A0B4K742_DROME Unreviewed; 2595 AA.
AC A0A0B4K742;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 63.
DE SubName: Full=Rab3 interacting molecule, isoform W {ECO:0000313|EMBL:AFH06487.2};
GN Name=Rim {ECO:0000313|EMBL:AFH06487.2,
GN ECO:0000313|FlyBase:FBgn0053547};
GN Synonyms=CG7301 {ECO:0000313|EMBL:AFH06487.2}, CG7305
GN {ECO:0000313|EMBL:AFH06487.2}, CG7321 {ECO:0000313|EMBL:AFH06487.2},
GN dm-Rim {ECO:0000313|EMBL:AFH06487.2}, Dmel\CG33547
GN {ECO:0000313|EMBL:AFH06487.2}, DmRIM {ECO:0000313|EMBL:AFH06487.2},
GN DRIM {ECO:0000313|EMBL:AFH06487.2}, RIM {ECO:0000313|EMBL:AFH06487.2},
GN rim {ECO:0000313|EMBL:AFH06487.2}, rim-1
GN {ECO:0000313|EMBL:AFH06487.2}, UNC-10/RIM
GN {ECO:0000313|EMBL:AFH06487.2};
GN ORFNames=CG33547 {ECO:0000313|EMBL:AFH06487.2,
GN ECO:0000313|FlyBase:FBgn0053547}, Dmel_CG33547
GN {ECO:0000313|EMBL:AFH06487.2};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AFH06487.2, ECO:0000313|Proteomes:UP000000803};
RN [1] {ECO:0000313|EMBL:AFH06487.2, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A.,
RA An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H.,
RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E.,
RA Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C.,
RA Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A.,
RA Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C.,
RA Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G.,
RA Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.,
RA Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2] {ECO:0000313|EMBL:AFH06487.2, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537568;
RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A.,
RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A.,
RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R.,
RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J.,
RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C.,
RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.;
RT "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster
RT euchromatic genome sequence.";
RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002).
RN [3] {ECO:0000313|EMBL:AFH06487.2, ECO:0000313|Proteomes:UP000000803}
RP GENOME REANNOTATION.
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [4] {ECO:0000313|EMBL:AFH06487.2, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537573;
RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R.,
RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M.,
RA Celniker S.E.;
RT "The transposable elements of the Drosophila melanogaster euchromatin: a
RT genomics perspective.";
RL Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002).
RN [5] {ECO:0000313|EMBL:AFH06487.2, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537574;
RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A.,
RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G.,
RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M.,
RA Karpen G.H.;
RT "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.";
RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002).
RN [6] {ECO:0000313|EMBL:AFH06487.2, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022;
RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D.,
RA Ashburner M., Anxolabehere D.;
RT "Combined evidence annotation of transposable elements in genome
RT sequences.";
RL PLoS Comput. Biol. 1:166-175(2005).
RN [7] {ECO:0000313|EMBL:AFH06487.2, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=17569856; DOI=10.1126/science.1139815;
RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.;
RT "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.";
RL Science 316:1586-1591(2007).
RN [8] {ECO:0000313|EMBL:AFH06487.2, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=17569867; DOI=10.1126/science.1139816;
RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M.,
RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A.,
RA Dimitri P., Karpen G.H., Celniker S.E.;
RT "Sequence finishing and mapping of Drosophila melanogaster
RT heterochromatin.";
RL Science 316:1625-1628(2007).
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DR EMBL; AE014297; AFH06487.2; -; Genomic_DNA.
DR RefSeq; NP_001247169.2; NM_001260240.2.
DR SMR; A0A0B4K742; -.
DR EnsemblMetazoa; FBtr0336719; FBpp0307700; FBgn0053547.
DR GeneID; 42150; -.
DR AGR; FB:FBgn0053547; -.
DR CTD; 42150; -.
DR FlyBase; FBgn0053547; Rim.
DR VEuPathDB; VectorBase:FBgn0053547; -.
DR OrthoDB; 2891597at2759; -.
DR BioGRID-ORCS; 42150; 0 hits in 3 CRISPR screens.
DR GenomeRNAi; 42150; -.
DR Proteomes; UP000000803; Chromosome 3R.
DR Bgee; FBgn0053547; Expressed in brain and 8 other cell types or tissues.
DR ExpressionAtlas; A0A0B4K742; baseline and differential.
DR GO; GO:0048788; C:cytoskeleton of presynaptic active zone; IBA:GO_Central.
DR GO; GO:0048786; C:presynaptic active zone; IDA:FlyBase.
DR GO; GO:0042734; C:presynaptic membrane; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0044325; F:transmembrane transporter binding; IBA:GO_Central.
DR GO; GO:0048791; P:calcium ion-regulated exocytosis of neurotransmitter; IBA:GO_Central.
DR GO; GO:0070073; P:clustering of voltage-gated calcium channels; IMP:FlyBase.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0007274; P:neuromuscular synaptic transmission; IMP:FlyBase.
DR GO; GO:0050806; P:positive regulation of synaptic transmission; IBA:GO_Central.
DR GO; GO:0042391; P:regulation of membrane potential; IBA:GO_Central.
DR GO; GO:0048167; P:regulation of synaptic plasticity; IMP:FlyBase.
DR GO; GO:0016079; P:synaptic vesicle exocytosis; ISS:FlyBase.
DR CDD; cd04031; C2A_RIM1alpha; 1.
DR CDD; cd04028; C2B_RIM1alpha; 1.
DR CDD; cd00065; FYVE_like_SF; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR010911; Rab_BD.
DR InterPro; IPR039032; Rim-like.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12157:SF21; RAB3 INTERACTING MOLECULE, ISOFORM F; 1.
DR PANTHER; PTHR12157; REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN; 1.
DR Pfam; PF00168; C2; 2.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00239; C2; 2.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50004; C2; 2.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50916; RABBD; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000803};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 4..130
FT /note="RabBD"
FT /evidence="ECO:0000259|PROSITE:PS50916"
FT DOMAIN 68..118
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 817..921
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1148..1269
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 2445..2563
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 141..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 280..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 542..632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 648..698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 923..965
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 999..1146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1292..1365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1401..1527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1539..1560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1610..1650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1754..1774
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1964..2243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2271..2397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 19..56
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 155..176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..388
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..447
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..564
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..615
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 667..695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..808
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 926..965
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1005..1065
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1092..1111
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1297..1336
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1344..1358
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1406..1420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1469..1524
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1610..1631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2008..2084
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2120..2241
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2299..2315
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2324..2360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2595 AA; 278058 MW; D105163C43C358E9 CRC64;
MDEMPDLSHL TPHERMQIEN VLMRQKQEEE KQNEIMRRKQ DEVVTLEMQI RQRSEQQKKA
GVELDATCHI CLKTKFADGV GHICHYCNIR CCARCGGKVT LRSNKVIWVC ILCRKKQELL
SKTGQWINKT AAQQDGFIRR IEPDGSSDIS QHPIVDPHDT TDKRPKLERT RSAAEKENLP
MQRAGSMLRR QYSQQEQPTN RRLSASDSGM DPVMSPGQQM QHHQQQQRAR MQPMNPQQAQ
QGYGMQQQQQ PRSGGAYPDD DPRYYQGELD GLMRQHPHLA HPSQVQPQHT PQSHSQQQQS
QHQQQHLMPQ QHRPSPQQHS QQQQQQQQHS QQFAARQQQH QQQQHQQQVQ QSYHAQIHQQ
PQQHPHPHSQ QQQHHQQMQH QHGQSVPQMG GYQKPPPLTR NLTISGGHAM DSSAYSQQQQ
QQQRRALAGS QYASQQQRSF SSSEEEFQHQ LLAAQGAVTV TAGSDYDGGR LQVRTSLDPW
RQQRSLNERD LLSSGGGGGG GVGGADFRHL SHATQRLYAS ADQRDRYELQ LQHRERLEQY
PLTRTARLDV QQRNSLNRSN HERQFSGGGA GVGPGGAGGG GAAGAYRRAP PLAAAGGGGS
SSSSTTSSSY YPQSKPQIVI GPGSGYDRGS GSMASMASAA AATAADAQGQ AARNSQRGGL
LGATRGGGGS SSVSSTEAAY WDEPATSSSS SAAQDSRRFT ERRIKKTVRF DAHDEEASIL
ASSSLPPVTA ILPSTAVDVG AATILSSGKS LDAVGVGGAD WSRWEAERQG SQDSATKDSG
IDTSSTFTSS EDSNRGDGPK NPVNWQTSAD NTRLIGHMIL RKYYDGEDIL GLKVNGGQPL
ATGGSVSGAG TGAAIGAGGP CGAIVEKVKR GSVADLEGRI RPGDEILEWN GRGLHNKSAD
EVYDIIDESR LDAQVELIVS RPIGSGGGSG GSSANVSPIS GASGGSANSV PARRSSANFP
HSGLASSMAG SAVVSSGGRY LQRKAPAVEA IEIHRDKPSV LITSPGSPDI HTSVSGPGSV
SGSGLRQRGG VGQTQRLGPS HSTHSHSSSG SGSGSGSSTS SVHAPASAHG PVHASASASG
SAPGGLHGTT TAGHHHHPHP HHYHPHQHPL PHPHQHQGPP AAHLQGHGVG GGIGMGSGSG
TTTQPIPIEG RLQLKLGYDQ NTLQLIVTLV CATGLSLRQS GAGRNPYAKV FLLPDRSHKS
KRRTKTVGTT CEPRWGQTFV YSGLRRCDLN GRLLEVTLWD YVRYGANDFI GEVVIDLAHH
ILDDEAEWYQ LQPHQDTSYL LRDEGSDVDG LILTPTDHLS PPSTMSRLSD SDTTSDCDID
GMTPGASISS MGSSASPPPL LELDLNERRS RRDMSPQGRK RVAGMVARDY RTVSGIGQSY
HNQASATGYY RRGGGNGVGS AIGPGGMSLS QRSHSAAPSD GYHSSGVGGA ASGGPAYGYR
STSPRRGSLS PPDDRYIDYP VLPVHGSSPN APSVYQGPGG VSSAAASASQ QQRFQSRSAT
ATPTGSPKKR QLPQVPQTSR SAMLRDRLGQ DFDERLASGG RFGRHRTRQP HHQATYRSTG
MGGWERHYTG LSDSDLHSMD ARMRPRHSLS PDKDFMGEFG DSDMESVVSV TSSAFSTQSE
RPRTSRGLSS SPAGVHPHAH DHTSTTPSSL VGYVRDHQDK SCSHCQNGSQ PVVLSTHHTL
HLTAAGLAIG ACQDPCCLAD AHPHPQHQPM GYGEPPSSDP AMCGECVDQH FLGGLTGPQL
NLGVVPTYHV HTPTPNAHRR ARGQMATPAP PPTQSVLRLS RQLSEDALVA AVPISEAKAQ
PTSILKKPKL ERRRLFHEGQ SRSLDYDDLH TKSWGRRRIR YEDEVMPSSG DYPYPHSNPY
SSYSPTAAMS RRYGSETNIR QSYMGANVDA NHPLSHSHFL VTDDKIVTIT YDSDVGWTRR
GVAPSLFRGA HRQRGLADPR NHMSLDLQRT SQQKLYGPAA PYLKRRRNLP HPPSAQNAHN
FSPMEPGSGM DGLNAAAAGM VEQGNGMGSG GAHNTTSTHN SNHHNSQASS VSVSQSHNQQ
LQQQQQLQQQ SVRQKGKEGT TAISGSMMAS EQLTKSSSGS GGATSAAAAG HLVVGGTNAN
NASSSSFANP QPPPPQQQQQ LHGSPNNLNN NNKRAPSSTP QQNTNTINDA NNLTLDATQQ
QSQQQQLQQP PNTCTNQNTN PTTTLTTTTT TSSNATNAAT TTTANATNAT TTATNPTTTT
TNNTNEPNAT TTTTTTNANA DADADADADA PLDAIDWDAI DAMLDDDFSE YDKDKNGAEE
AGGSKSAEGA GAEDKVDGSL SDTANDRKKG GGVDQERSPK GGSGMGKKSN STSQLSATEQ
EQYQAQFAIA GSSTSSAGHH HITLPPPHPY HQRQSRGSAG SIQRSVEVPP VPPVTRYSAG
SIHSITSSEG SSFSPSLRND GALNEFVDGL GPGQLVGRQV LGAPSLGDIQ LSLCHQKGCL
EVEVIRARGL QQKAQSKMLP APYVKVYLVS GKRCVDKMKT SSARRTLDPL YQQQLVFKQS
YTGCILQITV WGDYGRIEKK VFMGVAQIML DDLNLSNIVI GWYKLFGTTS LVSCPTNIGL
GSRRSSIASL DSLKL
//
