ID A0A0B5EIX6_STRA4 Unreviewed; 598 AA.
AC A0A0B5EIX6;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=GNAT family N-acetyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=SLNWT_1852 {ECO:0000313|EMBL:AJE82228.1};
OS Streptomyces albus (strain ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 /
OS NBRC 107858).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1081613 {ECO:0000313|EMBL:AJE82228.1, ECO:0000313|Proteomes:UP000031523};
RN [1] {ECO:0000313|EMBL:AJE82228.1, ECO:0000313|Proteomes:UP000031523}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 / NBRC 107858
RC {ECO:0000313|Proteomes:UP000031523};
RA Lu C.;
RT "Enhanced salinomycin production by adjusting the supply of polyketide
RT extender units in Streptomyce albus DSM 41398.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP010519; AJE82228.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B5EIX6; -.
DR KEGG; sals:SLNWT_1852; -.
DR Proteomes; UP000031523; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR000182; GNAT_dom.
DR PANTHER; PTHR43877; -; 1.
DR PANTHER; PTHR43877:SF1; N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13673; Acetyltransf_10; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS51186; GNAT; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Reference proteome {ECO:0000313|Proteomes:UP000031523}.
FT DOMAIN 1..151
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
FT DOMAIN 320..519
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT REGION 229..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..258
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 598 AA; 62772 MW; E6D016797FF12A38 CRC64;
MRIRDARPAE APELSALLRR SKAHWGYEAA FLDAIAEELT LDAAELAKRR VVVAEEERTG
ELLGLASLEG TAPRGALGLL FVEPERVRTG VGRTLYAHVL DRARELGFAS LTVDADPHAV
DFYRRLGAQP VPGPGPLPRL AVAVPARAPW ARAWTRGRRT VQLGNVAEFQ GQFSPLTAAA
REASAHYSCL AALTSPSPAA LVLPATVPPG WTALLARALG WSDPELYDGL GSGGAGDPGA
GDPTTGSRTA SGRTAPSPTV RGLTAEVLAR PALTARLRAL DLPVLPWGRT PATAELTGEP
LAPGALRHES KRAANALFHR LAPHCPGILV PRQRTAATRR EAARLLAASL RTGPGAVLKS
EQGVGGYRTH LLTSYRGLLP ALRSVPRGPL LVEEYVRGGA GGPRDLTFDG VVDAEGAVHA
VGTGVMAVRG TAYQGVTVGP GVVPAELDRI AVRFGLAVGR ELAATGHRGW FDVDFVRAPG
GRLAPTEINQ RLTGPSAAFV TAARLDEVRG GRHCVRALDH LPLGARLPDA QLLPWLTQVT
ARCARVGAVL LPSVPTAAYA AAPYLGVLIA ARDVDLLDAA EALLREAARD LGELFNSP
//
