ID A0A0B5EM33_STRA4 Unreviewed; 503 AA.
AC A0A0B5EM33;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:AJE80405.1};
GN ORFNames=SLNWT_0029 {ECO:0000313|EMBL:AJE80405.1};
OS Streptomyces albus (strain ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 /
OS NBRC 107858).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1081613 {ECO:0000313|EMBL:AJE80405.1, ECO:0000313|Proteomes:UP000031523};
RN [1] {ECO:0000313|EMBL:AJE80405.1, ECO:0000313|Proteomes:UP000031523}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 / NBRC 107858
RC {ECO:0000313|Proteomes:UP000031523};
RA Lu C.;
RT "Enhanced salinomycin production by adjusting the supply of polyketide
RT extender units in Streptomyce albus DSM 41398.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP010519; AJE80405.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B5EM33; -.
DR KEGG; sals:SLNWT_0029; -.
DR Proteomes; UP000031523; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07106; ALDH_AldA-AAD23400; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR044086; LUC3-like.
DR PANTHER; PTHR11699:SF263; ALDEHYDE DEHYDROGENASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000031523}.
FT DOMAIN 28..477
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 484..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 255
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 503 AA; 53543 MW; 97F999FB007019F2 CRC64;
MAAPVESPSA QPDLAVPFHT INGRPETSEE QSEIIDPATG EVFAQCPLAT GEQLDRAVAA
AQDASPAWAQ TGWAARSRAL TALAEAIRAE TEPLAHLLTR EQGKPLAHAR AEILRCAEIF
AQVAAYSEIT AVVLREDETA VVEQHFAPRG PTAVITPWNV PVGIAALRSA PFLQTGNTVV
LKPSPYTPLT TLRLGRIAAR VLPAGVFNVL STGDALAGRL TAHEDIAAVS FTGSVPTGRS
VMASAAPGLK HLGLELGGND PAIVLDDVDP QAVAPQIFRA AFANSGQICM AIKRVYAHES
IHDRLVEELA RLADAAVLGP GTNPRSEIGP VQNQAQHQRL RELLEETRAI PGVRLATARR
DVPERGYFLA PTVVADIRDG ARLVDEEQFG PVLPVVRFTD EDDALHRANA TRYGLSASVW
SASPGRAAAL AQRVEAGTVW INTHLVTDVH TPFGGWKDSG IGRVNGVRGL ESCLEGRVVF
RAKQPARRPA GESRPCTRTG SRT
//
