ID A0A0B5F746_STRA4 Unreviewed; 588 AA.
AC A0A0B5F746;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:AJE86252.1};
GN ORFNames=SLNWT_5876 {ECO:0000313|EMBL:AJE86252.1};
OS Streptomyces albus (strain ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 /
OS NBRC 107858).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1081613 {ECO:0000313|EMBL:AJE86252.1, ECO:0000313|Proteomes:UP000031523};
RN [1] {ECO:0000313|EMBL:AJE86252.1, ECO:0000313|Proteomes:UP000031523}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 / NBRC 107858
RC {ECO:0000313|Proteomes:UP000031523};
RA Lu C.;
RT "Enhanced salinomycin production by adjusting the supply of polyketide
RT extender units in Streptomyce albus DSM 41398.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809}.
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DR EMBL; CP010519; AJE86252.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B5F746; -.
DR KEGG; sals:SLNWT_5876; -.
DR Proteomes; UP000031523; Chromosome.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR019801; Glyco_hydro_35_CS.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000031523}.
FT DOMAIN 11..327
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 374..475
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 508..562
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 156
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 232
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 588 AA; 63867 MW; A4E1219A0DA72F68 CRC64;
MHEFRVGEDD FELDGRPLRL LSGALHYFRV HESQWGHRLA MLRAMGLNCV ETYVPWNLHE
PRPGEYRDLD ALGRFLDAAR RAGLWAIVRP GPYICAEWEN GGLPHWITGP LGPRARTRDA
VYGAAVARWF TALLPQVVTR QVDRGGPVLM VQVENEYGSY GSDARYLAQL RDLLLDLGVS
VPLFTSDGPE DHMLTGGSVP GVLATANFGS GARAAFATLR RHRPKGPLMC MEFWCGWFDH
WGAGHAVREP GDAAKALREI LECGASVNLY MAHGGTSFGG WAGANRAGEL HDGRLLPDVT
SYDYDAPIDE YGRPTPKFFA FREVLAAYAE EPPPGLPPAP PSLGAPVSVP VRERVPLAEV
LAALGGPETE GPLPPSFEEL DVDRGLVRYT VRVPGPRQPY PLSAPGLRDR AVVYVDGRRA
GVLTEEQPVL PEPVAGPAEV ELWTESLGRV GYGPRTGEPK GATGGLRHER QFLHGVRARG
LRLDAFDAAE RVRALPFTAA PGDGAAGLYR ASAEIRGAGD ARLRLPGWTR GFVWVNGFCL
GRYWSLGPQD SLYVPGPVLR EGPCEVWILE LEEAGGAVEL SGVSGPGR
//
