ID   A0A0B6X286_9BACT        Unreviewed;       677 AA.
AC   A0A0B6X286;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Peptidoglycan synthetase FtsI {ECO:0000313|EMBL:CDM67077.1};
DE            EC=2.4.1.129 {ECO:0000313|EMBL:CDM67077.1};
GN   ORFNames=PYK22_03126 {ECO:0000313|EMBL:CDM67077.1};
OS   Pyrinomonas methylaliphatogenes.
OC   Bacteria; Acidobacteriota; Blastocatellia; Blastocatellales;
OC   Pyrinomonadaceae; Pyrinomonas.
OX   NCBI_TaxID=454194 {ECO:0000313|EMBL:CDM67077.1, ECO:0000313|Proteomes:UP000031518};
RN   [1] {ECO:0000313|EMBL:CDM67077.1, ECO:0000313|Proteomes:UP000031518}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K22 {ECO:0000313|EMBL:CDM67077.1,
RC   ECO:0000313|Proteomes:UP000031518};
RA   Stott M.;
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDM67077.1, ECO:0000313|Proteomes:UP000031518}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K22 {ECO:0000313|EMBL:CDM67077.1,
RC   ECO:0000313|Proteomes:UP000031518};
RA   Lee K.C.Y., Power J.F., Dunfield P.F., Morgan X.C., Huttenhower C.,
RA   Stott M.B.;
RT   "Complete genome sequence of Pyrinomonas methylaliphatogenes type strain
RT   K22T.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CBXV010000008; CDM67077.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B6X286; -.
DR   STRING; 454194.PYK22_03126; -.
DR   OrthoDB; 9770103at2; -.
DR   Proteomes; UP000031518; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR   CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR   Gene3D; 1.10.150.770; -; 1.
DR   Gene3D; 3.30.10.20; -; 1.
DR   Gene3D; 3.30.450.330; -; 1.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005543; PASTA_dom.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03793; PASTA; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SMART; SM00740; PASTA; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR   SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 1.
DR   PROSITE; PS51178; PASTA; 1.
PE   4: Predicted;
KW   Glycosyltransferase {ECO:0000313|EMBL:CDM67077.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031518};
KW   Transferase {ECO:0000313|EMBL:CDM67077.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        32..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          616..675
FT                   /note="PASTA"
FT                   /evidence="ECO:0000259|PROSITE:PS51178"
SQ   SEQUENCE   677 AA;  73437 MW;  0B8BF1F35078B14C CRC64;
     MGVTPKRYVM FRGSAAHRTS EDSVVAGRRM RIVLGAFILW MGVIAGRLIY LQTSRHEELA
     ARARAQQLVQ IEIEPLRGTI IDRQGRELAR SIETDSFFAV PEEIEDVQTV ARRLAPLLGT
     EIGALASRLE SARAEGRRFV WLARKLDAER AAAVRALALR GVYELKEPKR FYPNGALAAH
     VLGFVSLDEE GLAGVERFHN ASLTGEEGRI WIERDAHRRS YESFEVAARE GNEIVLTLDQ
     TIQHWAEQAL QEAVERSQAR AGTAIVLDPK TGEILALANA PTFDPNEARA LPPDRLRNEA
     LQNIYEPGST FKIVSFAAAL EEGLARPDER IDCQMGAIVV AGRTVHDHHP FGILTLTEAL
     AKSSNVAAIK LGLRVGSARL YEYIRRFGFG AKTGVELPGE TAGLLRPVER WQPSSIGSIA
     IGQEIGVTPL QVAAAFAAVA NDGVRVAPHL VREVRSGDGA VVKRAQPEAR RVISAETART
     LRGMLEMVTL KGTARRAQLD GYTAAGKTGT AQKVDPRTHA YSKTKYVASF VGFAPASDPR
     VVIIVVIDEP RGAYHGGEVA APVFREIAER VLPYLDVAPD VIGPNLADQM GARHSEARVP
     QVAIERRGEM VLAHAQGAGF TMPDLRGQSL RDAARLCAQL GLSLVADGEG RVIAQEPEAG
     AAVRAGDTVR VLFARSE
//