ID A0A0B7NLB8_9FUNG Unreviewed; 1185 AA.
AC A0A0B7NLB8;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=DH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=PARPA_13701.1 scaffold 47024 {ECO:0000313|EMBL:CEP19386.1};
OS Parasitella parasitica.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Parasitella.
OX NCBI_TaxID=35722 {ECO:0000313|EMBL:CEP19386.1, ECO:0000313|Proteomes:UP000054107};
RN [1] {ECO:0000313|EMBL:CEP19386.1, ECO:0000313|Proteomes:UP000054107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 412.66 {ECO:0000313|EMBL:CEP19386.1,
RC ECO:0000313|Proteomes:UP000054107};
RA Ellenberger Sabrina;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN734024; CEP19386.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B7NLB8; -.
DR STRING; 35722.A0A0B7NLB8; -.
DR OrthoDB; 5100844at2759; -.
DR Proteomes; UP000054107; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001180; CNH_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041675; PH_5.
DR PANTHER; PTHR46572; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46572:SF1; RHO1 GUANINE NUCLEOTIDE EXCHANGE FACTOR TUS1; 1.
DR Pfam; PF00780; CNH; 1.
DR Pfam; PF15405; PH_5; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00036; CNH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50219; CNH; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054107}.
FT DOMAIN 482..673
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 823..1147
FT /note="CNH"
FT /evidence="ECO:0000259|PROSITE:PS50219"
FT REGION 61..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1185 AA; 133497 MW; EF07C560BB61DA60 CRC64;
MWNQSELPKL VGTANDRDSL DSSLNGLMRD VDSFISELNC EQQQQTQQHL YRMPTSARAH
SLQSQSRHQT PITANRAKTT CRSGHNNDRY NTQIASPSSQ TPYYLQQQQS RPPLRPTTAP
TSATLVEPNM SMPSITPHPY AVPPTPPSFS YLPSYNEPLS LYPNPGCNAN SDYVSTYLAS
NQKRNQLFLG EEKTAVSYGS DNSSCRNSSS SSIITADSTS NMSSSLKQNP SDSSRVGGSG
TNLHYSLSIS SATPSSCAAT DGTNTPPTTI ATSGKPPAFA FLSVLSKSFV KRVRSLENVR
ELFCANEYPE SFTGQEAIKM LYSLLDGIPE AYCIRVANAL MKSKPPLFEP IHYSQKSIIQ
GTVFNSSDEY YTLPEDMKNE DVPTGILTGL LECYTYQCIP GKGGCYAPRC PNKPEVFAME
FDIQDSAAAA ATTAKSRPHY YSADQMNRNG TATTAYGTQP QMAWAQKAPK ELLESLSKRE
ISRQEAINEM IYSEEVYKRD LDTLSEVIVA PLLRKSIIAS AQKREEFVHE VFGNYKELIE
VSTALFADLL ELQRQFELEC VPMIGDILIK HFAYFQDPFS RYCPRVSLAE YLVKEEERNN
PDFERFVVQV EKSKRMRRLA FRHFLLNPVT RMQRYPLLLE AILKKTDQDH PDYTYLCKCL
DMVKKVAAQS DSMAEIFKKR VEILEINDAI TFKQGEFQDL QLTDPHRRLY YQCDVKRRSN
GIEMTEKSDI HLFVFNHMIL MTKVRKAATT ATIMDEYRVW RRPIPLQMLH VSCASESGSS
SSHSILASSS STRNLLSTTT ASPSSYTPAG YVPLTFHHLG RRGGVYTFSC SLDEKQKLFA
AIEEARSLLK KRLGEDVYRV VSLDNTCFRY TSAAGSSSSN SISGYAKHGR VNCTVPFVSA
DNKRKLAVGT DTGIYFKDID EYGIRKVLSS ENVTRMAVLE RKSPGKLGQE LGQHHIYITG
APFGSKGSKE SKIPCSEDWV HDWQSVEPFV VQKEFYVGAE STNIHFLKSK LLIVCERGFE
IIDPENLSVG GRDIPDKGDP QFNFVHRQSD SLKPLAMYRV HDKFMLCYNK FAYYVNNRNG
SLVQRGPQKI PLLCEWEGNP DNIVFQYPYV IAFDHQFIEV RHVDTGDLVQ IIPGDQIRLT
HFHTTADATV IQGCMTHSQK PDIQDIFYLK LNAQRSGSFR KFIKQ
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