ID A0A0C1DYF5_9FLAO Unreviewed; 635 AA.
AC A0A0C1DYF5;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=OA93_04950 {ECO:0000313|EMBL:KIA99515.1};
OS Flavobacterium sp. KMS.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1566023 {ECO:0000313|EMBL:KIA99515.1, ECO:0000313|Proteomes:UP000031466};
RN [1] {ECO:0000313|EMBL:KIA99515.1, ECO:0000313|Proteomes:UP000031466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KMS {ECO:0000313|EMBL:KIA99515.1,
RC ECO:0000313|Proteomes:UP000031466};
RA Smith A.K., Newman J.;
RT "Flavobacterium sp. KMS.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIA99515.1}.
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DR EMBL; JSYP01000003; KIA99515.1; -; Genomic_DNA.
DR RefSeq; WP_039112031.1; NZ_JSYP01000003.1.
DR AlphaFoldDB; A0A0C1DYF5; -.
DR STRING; 1566023.OA93_04950; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000031466; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:KIA99515.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000031466}.
FT DOMAIN 12..68
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 70..462
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 519..598
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 635 AA; 71831 MW; FBE3DBF35EEAA6C4 CRC64;
MSYYKIENLE QYFKHYNKSV REPRKFWGKI AEENFTWYQQ WEKVVDFNMA DAEVKWFSEA
KVNITKNCID RHLSKRGEKT AIIFEPNDPS ESSLHITYNE LYERVSKMAN VLREQGIKKG
DRVCIYLPMI PELAVSVLAC ARIGAIHSVV FAGFSASAVT ARINDSECKM VITSDGGYRG
NKTIDLKAIV DEALETCPCV TKVLVAKRTK TEVKMKEGRD QWLQPLLDAA LDYNVAEIMD
AEDPLFILYT SGSTGKPKGM VHTTAGYMVY TAYTFKNVFA HEENDIFWCT ADIGWITGHS
YILYGPLLNG GTTVIFEGVP SYPDFSRFWE IIEKHKVTQF YTAPTAIRSL AKESLDYVQK
YPLKSLKVIG SVGEPINEEA WHWYNDHVGD KRCPVVDTWW QTETGGIMIS PIAFVTPTKP
TYATLPLPGI QPVLMDEKRN EIEGNQVVGS LCIKFPWPGI ARTIWGDHQR YKDTYFSAFP
GKYFTGDGAL RDEVGYYRIT GRVDDVVIVS GHNLGTAPIE DAINEHPAVA ESAIVGFPHD
IKGNALYGFV ILKETGEYRD RANLSKEINQ YISDHIGPIA KLDKIQFVSG LPKTRSGKIM
RRILRKIAEG DYSNFGDIST LLNPEIVEEI MKEKI
//
