ID A0A0C1GXU5_9RHOB Unreviewed; 1004 AA.
AC A0A0C1GXU5;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Sarcosine oxidase subunit alpha {ECO:0000313|EMBL:KIC44003.1};
GN ORFNames=RA28_13440 {ECO:0000313|EMBL:KIC44003.1};
OS Ruegeria sp. ANG-S4.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Ruegeria.
OX NCBI_TaxID=1577904 {ECO:0000313|EMBL:KIC44003.1, ECO:0000313|Proteomes:UP000031326};
RN [1] {ECO:0000313|Proteomes:UP000031326}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ANG-S4 {ECO:0000313|Proteomes:UP000031326};
RX PubMed=25755651; DOI=10.3389/fmicb.2015.00123;
RA Collins A.J., Fullmer M.S., Gogarten J.P., Nyholm S.V.;
RT "Comparative genomics of Roseobacter clade bacteria isolated from the
RT accessory nidamental gland of Euprymna scolopes.";
RL Front. Microbiol. 6:123-123(2015).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIC44003.1}.
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DR EMBL; JWLK01000005; KIC44003.1; -; Genomic_DNA.
DR RefSeq; WP_039529756.1; NZ_JWLK01000005.1.
DR AlphaFoldDB; A0A0C1GXU5; -.
DR STRING; 1577904.RA28_13440; -.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000031326; Unassembled WGS sequence.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000031326}.
FT DOMAIN 172..422
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 523..604
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 620..885
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 911..996
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 1004 AA; 109468 MW; 37F0BAC294186A28 CRC64;
MSTRLANHGR LIDRSKKVTF TFNGTSMQGF EGDTLASALL ANDQMMVGRS FKYHRPRGVV
ASGAEEPNAL VGLGQGNRFE PNQRATTTEL FNGLTSVSQN HWPNLEFDVG AINTHLSRFL
PAGFYYKMFI HPKPFWKHVY EPFIRQSAGL GKAPDKDSRD ADTYEHFYAF TDVLVIGGGI
AGLQAAKAAA ASGAKVLLIE QTAHWGGRAP VDGGTVGDEP VDKFVEQLVS ELETMDNVTM
RNRCMGAGVY DHGYVLGYER LTDHAPGAQG PRHRLWRIRA KQVVTATGAI ERPLSFAGND
VPGVILASAV RDYVVNWGVT PGDRVIIATN NDDAYRTAIT LKQAGVDVIR VVDARSSAGL
LAEEARQLGI RVDPGKAIAK VKGGKRVKKV ELCNQDGIGG AREEVDCDAV AMSGGWSPVV
HLWSHCGGKL IWDEANAHFR PDPKRPPLGA DGDGFVVAAG SANGPLALGD VLTDAHAAGK
AAAKAAGHKP KNTKAPSGDA TEEAAMEPVW LMPANADIQL RMKSWLDFQN DVKVSDVQLA
AREGYESVEH TKRYTTLGMA TDQGKLSNIN GLAILADALD AEIPKVGTTT FRPPYTPISM
GAIGGEARGE VFQPIRRTPM HDWHDKNGAD WEPVGHWRRT YAYTRPGESV HDAVNREVKN
TRENLGLLDA STLGKLIVKG PDAGKFLDMM YTNMMSTLKV GKCRYGLMCS ENGFLIDDGV
VARIDDDTWL CHTTTGGAER IHGHMEEWLQ TEWWDWKVYV ANVTEQYAQI AVVGPNARKV
LEKLGGMDVS KEALPFMEWR DGKIGDFDCR AYRVSFSGEL SYEIAVAASH GQAFWDALME
AGKEFGVMPY GTECLHILRA EKGFIMIGDE TDGTVIPQDL GLNWALSKKK EDYLGKRAHL
RSHMADPDRW KLVGLETVDG SVIPDGAYAV GEGVNANGQR NVIGRVTSTY YSANLGKGIA
MGLIKHGPDR MGEIVEFPGT DDKTYKAKIV DPIFFDKDGE KQNV
//
