ID   A0A0C1UCW9_9ACTN        Unreviewed;       474 AA.
AC   A0A0C1UCW9;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:KIE50614.1};
GN   ORFNames=MB52_05515 {ECO:0000313|EMBL:KIE50614.1};
OS   marine actinobacterium MedAcidi-G1.
OC   Bacteria; Actinomycetota; Actinomycetes.
OX   NCBI_TaxID=1550399 {ECO:0000313|EMBL:KIE50614.1, ECO:0000313|Proteomes:UP000031399};
RN   [1] {ECO:0000313|EMBL:KIE50614.1, ECO:0000313|Proteomes:UP000031399}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mizuno C.M., Rodriguez-Valera F., Ghai R.;
RT   "Novel reconstructed genomes of marine planktonic Acidimicrobiales.";
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an aldehyde + H2O + NAD(+) = a carboxylate + 2 H(+) + NADH;
CC         Xref=Rhea:RHEA:16185, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:17478, ChEBI:CHEBI:29067, ChEBI:CHEBI:57540,
CC         ChEBI:CHEBI:57945; EC=1.2.1.3;
CC         Evidence={ECO:0000256|ARBA:ARBA00024149};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KIE50614.1}.
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DR   EMBL; JUEM01000014; KIE50614.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0C1UCW9; -.
DR   Proteomes; UP000031399; Unassembled WGS sequence.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProt.
DR   GO; GO:0070887; P:cellular response to chemical stimulus; IEA:UniProt.
DR   CDD; cd07138; ALDH_CddD_SSP0762; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR42804; ALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR42804:SF1; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          13..470
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
SQ   SEQUENCE   474 AA;  49826 MW;  7C8B98B29652908C CRC64;
     MNDRSEIYVD GNWVASSGVE SISVINPSTE EIIGSTPAGT KEDVDLAVKA AREAFPGWSE
     TSLEERLSYI ENLAAKLGEK SAEIGELISQ EVGMPGKMSM MIQAGLPAAT TASVSGTARE
     FPFEETIGRS LVTREAVGVV GCITPWNYPL HQIMAKVAPA MAVGCTVVLK PSEVAPLNAF
     LLAEIIHELN FPKGVFNLVS GVGPVVGEAI AAHPDVDMIS FTGSTRAGTR VAEIAAANVT
     RVHQELGGKS ANIILDDADL SAAIPSAVGA CFLNSGQTCS ALTRLLVPSS KMDEAAELAA
     QAAAGFTVGP ADDETSKLGP LVSQAQWDRV QNYIKTGIDE GAALVTGGLG KPDGLDSGYF
     VKPTVFANVE NSMTIAQEEI FGPVLSIIGY EDDDDAIRIA NDSDYGLSGG VWSSDNERAL
     KVAKKLRTGE VDMNGSFLNT DAPFGGYKKS GNGRELGRFG MYEFVEAKQI NLPL
//