ID A0A0C1XER9_9ACTN Unreviewed; 446 AA.
AC A0A0C1XER9;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Polyketide synthase {ECO:0000313|EMBL:KIF73258.1};
DE Flags: Fragment;
GN ORFNames=QR77_03320 {ECO:0000313|EMBL:KIF73258.1};
OS Streptomyces sp. 150FB.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1576605 {ECO:0000313|EMBL:KIF73258.1, ECO:0000313|Proteomes:UP000031584};
RN [1] {ECO:0000313|EMBL:KIF73258.1, ECO:0000313|Proteomes:UP000031584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=150FB {ECO:0000313|EMBL:KIF73258.1,
RC ECO:0000313|Proteomes:UP000031584};
RA Tarkka M.T., Feldhahn L., Kruger D., Buscot F., Wubet T.;
RT "Genome sequence of the mycoparasite antagonist Streptomyces sp. strain FB
RT 150.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIF73258.1}.
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DR EMBL; JTHL01000001; KIF73258.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C1XER9; -.
DR STRING; 1576605.QR77_03320; -.
DR Proteomes; UP000031584; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR015083; Polyketide_synth_docking.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF51; PHENOLPHTHIOCEROL_PHTHIOCEROL POLYKETIDE SYNTHASE SUBUNIT E; 1.
DR Pfam; PF08990; Docking; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Reference proteome {ECO:0000313|Proteomes:UP000031584};
KW Transferase {ECO:0000256|ARBA:ARBA00023315}.
FT DOMAIN 33..446
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT NON_TER 446
FT /evidence="ECO:0000313|EMBL:KIF73258.1"
SQ SEQUENCE 446 AA; 47022 MW; 6CE5DD61BB6E8ABF CRC64;
MTEDKKLLDY LRRATAELGQ TKAALREALD ARHEPIAIVS MDCRYPGGVE SPEDLWRLVA
DGTDAITEWP TNRGWDLDGR YDPDPERTGT SYTRNGGFLH DAGQFDAGFF GISPREALAM
DPQQRLLLEA AWTALERGGF DPKSLHNTRT GVFVGAIGNG YGFRSKDVPE LQGLLDTGTH
DSVVSGRISY VLGLEGPAVS IDTACSSSLV AIHLAVQALR TGECSLALAG GITVMATQDA
FVAFSRQRGL AADGRCKSFA DAADGTGWSE GAGVLVLERL SDARRNGHEV LAVIRGSAIN
QDGASNGLSA PNGPSQQRVI KDALANAQLS VGDVDVVEAH GTGTSLGDPI EAQALLATYG
KHRDRPLWLG SLKSNIGHTS AAAGVGGVIK MVMAMRNGVL PKTLHVDAPS TAVDWTAGNV
RLLTEARAWD HEGAPCRAGV SAFGVS
//
