ID A0A0C2CCL5_9BILA Unreviewed; 448 AA.
AC A0A0C2CCL5;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Ion channel {ECO:0000313|EMBL:KIH54068.1};
DE Flags: Fragment;
GN ORFNames=ANCDUO_15787 {ECO:0000313|EMBL:KIH54068.1};
OS Ancylostoma duodenale.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=51022 {ECO:0000313|EMBL:KIH54068.1, ECO:0000313|Proteomes:UP000054047};
RN [1] {ECO:0000313|EMBL:KIH54068.1, ECO:0000313|Proteomes:UP000054047}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Zhejiang {ECO:0000313|EMBL:KIH54068.1,
RC ECO:0000313|Proteomes:UP000054047};
RA Mitreva M.;
RT "Draft genome of the parsitic nematode Ancylostoma duodenale.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC ECO:0000256|RuleBase:RU003857}.
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DR EMBL; KN739784; KIH54068.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C2CCL5; -.
DR Proteomes; UP000054047; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF338; OPEN RECTIFIER POTASSIUM CHANNEL PROTEIN 1-LIKE PROTEIN; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054047};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 136..180
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 246..318
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KIH54068.1"
SQ SEQUENCE 448 AA; 51183 MW; 57F1C63C5CEF933E CRC64;
LINVIFSLSH ILLLSSYVSF IVASAAAFFI TESLNSDRFR RQWQRRLASD RNSFVVKELL
PEIFNNTKLL LYIHDQKSQY LTAIMNERLE VYENQLKLRP PMPTLPCTFP NALLRFADEL
LYSLGQNKTV HLLLEVFSTI TTIGYGYIYP VTHAGRMLSI FISLIGIPFT IVVIKDVAYL
IAKLMNYPCE LLAKCWVAFR FCTLRPVDED ELDRKLHGEH AERKDYRLHN MERLLAIPVT
VAVFALIGWI CVGCFIVHLY MPNHDTSITF YFIFNSLATI GVGDIEPGRH PLVLLLLFIY
LLIGLSIVSL FINLLHTKFS RAYWLPGRMY MPLRSHELPA TQTLASFDSY EEMGVQSECP
INHFTTLGVL QADDKCPLLG ISRREFAYMD ANTQTERTIP HGYIPPPIPR SPSAVVLPYP
HTSHEDVNSL IVETYGVKPA RLIIKPSK
//
