ID A0A0C2E0F0_9BILA Unreviewed; 711 AA.
AC A0A0C2E0F0;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=ANCDUO_00849 {ECO:0000313|EMBL:KIH68817.1};
OS Ancylostoma duodenale.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=51022 {ECO:0000313|EMBL:KIH68817.1, ECO:0000313|Proteomes:UP000054047};
RN [1] {ECO:0000313|EMBL:KIH68817.1, ECO:0000313|Proteomes:UP000054047}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Zhejiang {ECO:0000313|EMBL:KIH68817.1,
RC ECO:0000313|Proteomes:UP000054047};
RA Mitreva M.;
RT "Draft genome of the parsitic nematode Ancylostoma duodenale.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN726286; KIH68817.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C2E0F0; -.
DR Proteomes; UP000054047; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47958; ATP-DEPENDENT RNA HELICASE DBP3; 1.
DR PANTHER; PTHR47958:SF26; EUKARYOTIC INITIATION FACTOR 4A-III; 1.
DR Pfam; PF00270; DEAD; 3.
DR Pfam; PF00271; Helicase_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:KIH68817.1};
KW Hydrolase {ECO:0000313|EMBL:KIH68817.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054047}.
FT DOMAIN 151..324
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 350..521
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 566..711
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 134..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 333..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..163
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..362
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 711 AA; 79433 MW; 7F0D650E55263399 CRC64;
MASATDVLPN EFNEDRVMFC GPRASIPTTF FSERNIVDFS KTVLDQVDVA DDCVQALVLV
STRDVAVQIH NEMKRIAETN QIKVHACVGG TPLFEEKLSL QRGAHVIVGT PGRVDHMIKL
GFLHSLNAVI YNESEERDVP TPESGVDAGE EVQDSEGDDD EVDAQTFDPQ RKALLLASVA
SLVDASKREA QVLVVIPRQS LIEQIYEDLR SSLNNSGISV YASTEKTKIQ DDNHIITAGV
HVLMGTPRRV CDLIKREALV TNFLKVLVMY DSKCMFGRSF KETISSIFGS VPKDVQMGIC
FCTSTLPRSQ RMLEQFREGL PVDSLNAVIY NESEERDVPT PESGVEAGEE LQDSEGDDDE
VDAQTFDPQR KALHLASVAS LVDVSKREAQ VLVVISRQSL IEQIYEDLRI SLNNSGISVY
ASTEKTKIQD DNHIITAGVH VLIGTPRRVC DLIKRDVLDA EHIRAIVMDT PEELFCKGFI
DQTRSIVQAL PDKVQVVSLS GKAYLNNLKF DEGSVTKVER PDKFLLENVR HFYIEVIRDE
LNTQLKECQG TNRSQLMDKK RVQFDVLCDL YPIMESRKSV ILCNGKKKAL RLHERITSKN
FTVTCLAGRM KRTKRGEELE RFESASTAVA IVTQDMADYF RDKQVSIVVN YDMPRRLKSY
VRCVGWSGSG GVERVVVNLI GSKSGIRLME TVKAAYGVPV KEICSRSDIV L
//
