ID   A0A0C2JHN2_9ACTN        Unreviewed;       315 AA.
AC   A0A0C2JHN2;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=von Willebrand factor A {ECO:0000313|EMBL:KIH98395.1};
GN   ORFNames=LP52_13230 {ECO:0000313|EMBL:KIH98395.1};
OS   Streptomonospora alba.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Nocardiopsaceae; Streptomonospora.
OX   NCBI_TaxID=183763 {ECO:0000313|EMBL:KIH98395.1, ECO:0000313|Proteomes:UP000031675};
RN   [1] {ECO:0000313|Proteomes:UP000031675}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIM 90003 {ECO:0000313|Proteomes:UP000031675};
RX   PubMed=25601074; DOI=10.1016/j.chembiol.2014.11.017;
RA   Metelev M., Tietz J.I., Melby J.O., Blair P.M., Zhu L., Livnat I.,
RA   Severinov K., Mitchell D.A.;
RT   "Structure, bioactivity, and resistance mechanism of streptomonomicin, an
RT   unusual lasso Peptide from an understudied halophilic actinomycete.";
RL   Chem. Biol. 22:241-250(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KIH98395.1}.
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DR   EMBL; JROO01000026; KIH98395.1; -; Genomic_DNA.
DR   RefSeq; WP_040273721.1; NZ_JROO01000026.1.
DR   AlphaFoldDB; A0A0C2JHN2; -.
DR   STRING; 183763.LP52_13230; -.
DR   OrthoDB; 8882959at2; -.
DR   Proteomes; UP000031675; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR024163; Aerotolerance_reg_N.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR22550; SPORE GERMINATION PROTEIN; 1.
DR   PANTHER; PTHR22550:SF19; UPF0353 PROTEIN RV1481; 1.
DR   Pfam; PF07584; BatA; 1.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031675};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        56..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        288..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          87..275
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
SQ   SEQUENCE   315 AA;  33199 MW;  BFB06EC99DA773CE CRC64;
     MTFLSPGWLW LLLALAALVA AYVVLQFRRR EDTLRFTNLS LLDRVAPRRA SWPRHIGAVL
     FFLAVAALIG AMARPAMPVE VPRERATIMV AIDVSPSMAA NDVDPNRLSA AKESARGFVD
     SLPDRFNVGL VAFSSTASVI SSPTQDHQAV TDSIETLQMS PGTAIGEGVF TSLESIRSFD
     EEAGDNPPPS AIVLLSDGEN TSGRPITSAG GAASDIGVPV STIAFGTGAA IIEINGEPVE
     ADIDKGALER LAADTSGHFY EAESEAELSD VYDDIGSSLG SETVDREIVT RFVLVGLILA
     AAGAVASMVW SQRVP
//