ID A0A0C5BTH8_9MICO Unreviewed; 409 AA.
AC A0A0C5BTH8;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=ROK family transcriptional regulator {ECO:0000313|EMBL:PPI14557.1};
GN ORFNames=C5C51_08335 {ECO:0000313|EMBL:PPI14557.1}, VT73_01650
GN {ECO:0000313|EMBL:KKM46981.1};
OS Rathayibacter toxicus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Rathayibacter.
OX NCBI_TaxID=145458 {ECO:0000313|EMBL:KKM46981.1, ECO:0000313|Proteomes:UP000052979};
RN [1] {ECO:0000313|EMBL:KKM46981.1, ECO:0000313|Proteomes:UP000052979}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FH142 {ECO:0000313|EMBL:KKM46981.1,
RC ECO:0000313|Proteomes:UP000052979};
RG Consortium for Microbial Forensics and Genomics (microFORGE);
RA Knight B.M., Roberts D.P., Lin D., Hari K., Fletcher J., Melcher U.,
RA Blagden T., Luster D.G., Sechler A.J., Schneider W.L., Winegar R.A.;
RT "Draft genome sequence of Rathayibacter toxicus strain FH-142 (AKA 70134 or
RT CS 32), a Western Australian isolate.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PPI14557.1, ECO:0000313|Proteomes:UP000237966}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FH99 {ECO:0000313|EMBL:PPI14557.1,
RC ECO:0000313|Proteomes:UP000237966};
RA Davis E.W.II., Tabima J.F., Weisberg A.J., Lopes L.D., Wiseman M.S.,
RA Wiseman M.S., Pupko T., Belcher M.S., Sechler A.J., Tancos M.A.,
RA Schroeder B.K., Murray T.D., Luster D.G., Schneider W.L., Rogers E.,
RA Andreote F.D., Grunwald N.J., Putnam M.L., Chang J.H.;
RT "Bacteriophage NCPPB3778 and a type I-E CRISPR drive the evolution of the
RT US Biological Select Agent, Rathayibacter toxicus.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKM46981.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LBFI01000011; KKM46981.1; -; Genomic_DNA.
DR EMBL; PSWU01000012; PPI14557.1; -; Genomic_DNA.
DR RefSeq; WP_027691700.1; NZ_PSXN01000010.1.
DR AlphaFoldDB; A0A0C5BTH8; -.
DR STRING; 145458.APU90_08570; -.
DR GeneID; 66873739; -.
DR KEGG; rtc:APU90_08570; -.
DR KEGG; rtx:TI83_08510; -.
DR PATRIC; fig|145458.7.peg.1940; -.
DR eggNOG; COG1940; Bacteria.
DR OrthoDB; 4083144at2; -.
DR Proteomes; UP000052979; Unassembled WGS sequence.
DR Proteomes; UP000237966; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000835; HTH_MarR-typ.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF177; N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF12802; MarR_2; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000052979}.
FT DOMAIN 14..60
FT /note="HTH marR-type"
FT /evidence="ECO:0000259|Pfam:PF12802"
SQ SEQUENCE 409 AA; 42763 MW; 1329A2E15BF55D2A CRC64;
MKRGTNLPAV AGYNQMLVLD LIRRAPDGIS RIELTHRTGL SAQTLSNVAR RLLQDGLVRE
TGKEVNGPGK PRTILQLKPD ARCAVGVHLD PTVTTSVVLD LAGRVLARAT MRTPRGVPAE
EIIDRLSASV TTLIASSGVA ADRILGVGVA SPGPLDPERG RVFDPPLLEE WRDVSLGAAL
SRSTGCEVYV EKDVTAAIVA ETWTSPPDDM GNALLFYYGT GVGAGLVVNG AVVRGSSGNP
GDIGHLIVDP DGPLCRCGTR GCLGDSVSPL ALVREAVGCG LVTGPSTGLD AVSVDLAFSR
LLAQVEQGHQ EAIAIVERAA RRIARGVLHL VGVLDLDQVI FGGPFWQRIA GVVLDVVPRA
VAHDPASMLT HGIQLRSSRF GADIAALGAA CVVLDRSLSP RAANLLIET
//
