ID A0A0C5VMS8_9GAMM Unreviewed; 351 AA.
AC A0A0C5VMS8;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Zn-dependent alcohol dehydrogenase {ECO:0000313|EMBL:AJQ96037.1};
DE EC=1.1.1.1 {ECO:0000313|EMBL:AJQ96037.1};
GN ORFNames=YC6258_04001 {ECO:0000313|EMBL:AJQ96037.1};
OS Gynuella sunshinyii YC6258.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Saccharospirillaceae; Gynuella.
OX NCBI_TaxID=1445510 {ECO:0000313|EMBL:AJQ96037.1, ECO:0000313|Proteomes:UP000032266};
RN [1] {ECO:0000313|EMBL:AJQ96037.1, ECO:0000313|Proteomes:UP000032266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YC6258 {ECO:0000313|EMBL:AJQ96037.1,
RC ECO:0000313|Proteomes:UP000032266};
RA Khan H., Chung E.J., Chung Y.R.;
RT "Full genme sequencing of cellulolytic bacterium Gynuella sunshinyii
RT YC6258T gen. nov., sp. nov.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072, ECO:0000256|RuleBase:RU361277}.
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DR EMBL; CP007142; AJQ96037.1; -; Genomic_DNA.
DR RefSeq; WP_044618150.1; NZ_CP007142.1.
DR AlphaFoldDB; A0A0C5VMS8; -.
DR STRING; 1445510.YC6258_04001; -.
DR KEGG; gsn:YC6258_04001; -.
DR PATRIC; fig|1445510.3.peg.3975; -.
DR HOGENOM; CLU_026673_20_2_6; -.
DR OrthoDB; 9771084at2; -.
DR Proteomes; UP000032266; Chromosome.
DR GO; GO:0004022; F:alcohol dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd05283; CAD1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR047109; CAD-like.
DR InterPro; IPR029752; D-isomer_DH_CS1.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR42683; ALDEHYDE REDUCTASE; 1.
DR PANTHER; PTHR42683:SF85; CINNAMYL ALCOHOL DEHYDROGENASE 6-RELATED; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
DR PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:AJQ96037.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000032266};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 11..343
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 351 AA; 38184 MW; A5668ECA9D21EE00 CRC64;
MSIVKAFGAV SPTSGVAAMK IERRKLREND VAIEIDYCGV CHSDLHYVEN DWGITRYPIV
PGHEIIGHVT AVGNSVTRYK PGDIVGVGCL VDSCKECSAC DHGLEQYCEN GMVGTYGGVD
RIDHTPTYGG YSENIVVREE FVLSIPETLD RASAAPLLCA GITTYSPLRH VGVKAGDKVG
VIGMGGLGHM GVKFAKALGA EVTLFTRSKT KEAEAKKQGA DHVVVSTDAA QMSAVANTFD
YLLDTIPVTH DFNPYLKCLK YDGKHMVVGQ LSPLEPALGL GALVTKRRSL MGSMIGGIAE
TQEMLEFCAE HNIRCDVEML DIENINQAYE RMKKGDVRYR FVIDMKSLKQ D
//
