ID A0A0C5VSU1_9GAMM Unreviewed; 985 AA.
AC A0A0C5VSU1;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=YC6258_05211 {ECO:0000313|EMBL:AJQ97241.1};
OS Gynuella sunshinyii YC6258.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Saccharospirillaceae; Gynuella.
OX NCBI_TaxID=1445510 {ECO:0000313|EMBL:AJQ97241.1, ECO:0000313|Proteomes:UP000032266};
RN [1] {ECO:0000313|EMBL:AJQ97241.1, ECO:0000313|Proteomes:UP000032266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YC6258 {ECO:0000313|EMBL:AJQ97241.1,
RC ECO:0000313|Proteomes:UP000032266};
RA Khan H., Chung E.J., Chung Y.R.;
RT "Full genme sequencing of cellulolytic bacterium Gynuella sunshinyii
RT YC6258T gen. nov., sp. nov.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21)
CC family. {ECO:0000256|ARBA:ARBA00006434}.
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DR EMBL; CP007142; AJQ97241.1; -; Genomic_DNA.
DR RefSeq; WP_044619030.1; NZ_CP007142.1.
DR AlphaFoldDB; A0A0C5VSU1; -.
DR STRING; 1445510.YC6258_05211; -.
DR KEGG; gsn:YC6258_05211; -.
DR PATRIC; fig|1445510.3.peg.5174; -.
DR HOGENOM; CLU_000445_22_1_6; -.
DR OrthoDB; 9764438at2; -.
DR Proteomes; UP000032266; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd10322; SLC5sbd; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 1.20.1730.10; Sodium/glucose cotransporter; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038377; Na/Glc_symporter_sf.
DR InterPro; IPR001734; Na/solute_symporter.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50283; NA_SOLUT_SYMP_3; 1.
DR PROSITE; PS50112; PAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000032266};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 468..490
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 626..670
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 759..976
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 985 AA; 110154 MW; 59A677D0000B8EE2 CRC64;
MTFSLSLLFA IGFGYLLLLF LLAHVVEKEW IAREWARHPL VYVLSIGVYC SAWAYFGTTG
LAYEYGYGYL TYYMGLSAAF LLYPFLLKPF LKITKNHSLG SLADVFAFRY HSRWAGTATT
ICMLLAILPL LALQIQAITD ATVILAPDTN ATPVGLAFCA MMIAFTTLYG ARQIHPRERH
RSLIFAIAFE SFFKLLMFVG LGIVAVFYVF ETPEKLQQWL NGPGFILRNR LNTMPIQTWM
LMSLLFIFAP LTMPHLFQAL LRENRNPTHL RYATWAVPIY LFLMALPVLP IMWAGMYLGQ
PTNPEFYSLA LGLGLQSPVI TILAYLGGVS AASGLLIVAT LAMASMTLNH VILPIHTPKG
DEDIYHWLLW TRRGLIVTII LAAYLVYMLL GQIHNLSSLG IASFVGVLQF VPGIIGTVFW
SRANRKGFLT GLVAGMLIWF ISIFYPLLVD SFSLTYRLPL RFALSESAWA YATSISISVN
LVLFLVVSWF TETSEEEKKA ARACSQDALA DTKRRQLVAR SSDQITEALS TALGKVSAER
EVNRVLKELN LPVGEYRPFA LRRMRDRIET NLSGLMGPSV AQTIVQRYLP YASDDEFGKE
DINLIESQLE GYHTQLTGLA AELDNLRRYH RQTLENLPVG VCSIGSDTEV LMWNPIMTEI
TGIEAKDIVG SHLNSLPLQW QTLLSRFMQG LSTHAYKKEL VIGSRKRWYN LHKASLPQGE
KTLSEGTVIL VEDQTEIQML EDELVHTERL ASIGSLAAGV AHEIGNPVTG IDCLAQDLLY
ESDSPMVKEA AEQIREQTRR VTQIVQSLVN YAHAGSTTGK SEHIAHPLHM IVHEAIKLLE
LSKKSRDVEF INNVPQQVEV ICDPHRLSQV FINLLNNARD ASEPGSYVAV NLHEPENNHF
VTVEVLDRGS GINPEHLDHI FEPFFTTKDV GKGTGLGLWI AYSIVEEHYG QIQVESPAFK
VEGIGTSVII TLPKANRPSN PEEQL
//
