ID   A0A0C9M5I3_9FUNG        Unreviewed;      1012 AA.
AC   A0A0C9M5I3;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein-like {ECO:0000313|EMBL:GAN04811.1};
GN   ORFNames=MAM1_0074c04276 {ECO:0000313|EMBL:GAN04811.1};
OS   Mucor ambiguus.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX   NCBI_TaxID=91626 {ECO:0000313|EMBL:GAN04811.1};
RN   [1] {ECO:0000313|EMBL:GAN04811.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NBRC 6742 {ECO:0000313|EMBL:GAN04811.1};
RA   Takeda I., Yamane N., Morita T., Tamano K., Machida M., Baker S., Koike H.;
RT   "Draft genome sequence of an oleaginous Mucoromycotina fungus Mucor
RT   ambiguus NBRC6742.";
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DF836363; GAN04811.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0C9M5I3; -.
DR   STRING; 91626.A0A0C9M5I3; -.
DR   OrthoDB; 24739at2759; -.
DR   Proteomes; UP000053815; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   CDD; cd00821; PH; 1.
DR   CDD; cd00160; RhoGEF; 1.
DR   Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000219; DH-domain.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR12673; FACIOGENITAL DYSPLASIA PROTEIN; 1.
DR   PANTHER; PTHR12673:SF159; RAC GUANINE NUCLEOTIDE EXCHANGE FACTOR JJ; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00621; RhoGEF; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00325; RhoGEF; 1.
DR   SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50010; DH_2; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053815}.
FT   DOMAIN          134..343
FT                   /note="DH"
FT                   /evidence="ECO:0000259|PROSITE:PS50010"
FT   DOMAIN          376..478
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          45..68
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          95..117
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          763..978
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..68
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        763..855
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        876..903
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        932..978
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1012 AA;  114707 MW;  7025A67E4D2E8043 CRC64;
     MKSALLQHPQ QQHDINDHHH MQQNCCCCCC YCCCYHQQSS SSSGSNNVVS SSSPPPPPQI
     PPWSSFSPPS PCDVKPTLDS ICSCCSCISH DQDTPTQAED EQEPENQHST GCTTPTMDEH
     HLKMTEAADK LQRKKMHAIE ELLQTERDYV QDLSYLVQVC LEVLSRQTWI APDHKSIIIR
     NSHDILSFHK QFIISYDTLS VYNCNWSRIA RTFLDQIGQF SLYKHYCDLH AEAWALLSEY
     RDRPEWACFL KDCTILDSYS IPLNLNTLST TAYTTPTAPV EQQQQAKKLH FEDYLIKPVQ
     RICRYQLLIK EIIRYTSPHT AEYDLWNSVL AEMQDIVGEI DDLKFQREMK ERTDRFIERL
     DGDWRISKRH VSQLGNLLLA GAIEITYSAL GQSVSKPRYL GCFIFQTYII MVRPKKVTSY
     EPKHWFPLRM ADFEDLGDIE GQREHAFVVK CKKHTFAFSA SCSQEKQLWV KKLQEAIVTA
     KIEASDENLS AQDYIVSSLP GITSKRSPQS IRLSRSFTNI LDMTLAGAHA HMNSSNDQIL
     SFSERKTLRR SASTSIQFED IMRMTQPSIT TVEPPPPPPP PLLPIITNAN HQDSNNSSIL
     KKRYSADYSY HHPSPNSGFA LKPRNNSEMY IKPDAFGGKR RPSSLDLLSF SATTTSNTSM
     IGKMSFQFKS NHQNALRVTV DHKLRDVCTQ EYLRSRAWHM RDREHNASLQ SSIDLLSLST
     TADSHLNSPV IGNANSNNND LLLKKRKSSS FIRSSASSFS LMIPKRTSES RQSNSSRLQQ
     QQIPSEDVQS NRSSSCASSM DRCVSPMTNK SNNSRRPSQS SQLLRHMSQN RGCFSESPHS
     FESSEYSFAT SQHQKRLEHS PSRRSILVGK VKKAASVDSK TSKLKWPRHK QQQQHEELTQ
     LKISDRPCKT TTTIASDNNE EQDDDNNEQE ENKGVQQGGG DLQTTLSAFA YASTPPPPVS
     KRQSQLLHST TKDGATSNNK WKNRLSLIRP TAASFLKLNN NSTSNTAIVH GT
//