ID A0A0C9MNX2_SPHPI Unreviewed; 862 AA.
AC A0A0C9MNX2;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SP6_09_00110 {ECO:0000313|EMBL:GAN12401.1};
OS Sphingomonas paucimobilis NBRC 13935.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1219050 {ECO:0000313|EMBL:GAN12401.1, ECO:0000313|Proteomes:UP000032025};
RN [1] {ECO:0000313|EMBL:GAN12401.1, ECO:0000313|Proteomes:UP000032025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 13935 {ECO:0000313|EMBL:GAN12401.1,
RC ECO:0000313|Proteomes:UP000032025};
RA Hosoyama A., Hashimoto M., Hosoyama Y., Noguchi M., Uohara A., Ohji S.,
RA Katano-Makiyama Y., Ichikawa N., Kimura A., Yamazoe A., Fujita N.;
RT "Whole genome shotgun sequence of Sphingomonas paucimobilis NBRC 13935.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAN12401.1}.
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DR EMBL; BBJS01000009; GAN12401.1; -; Genomic_DNA.
DR RefSeq; WP_042468397.1; NZ_BBJS01000009.1.
DR AlphaFoldDB; A0A0C9MNX2; -.
DR Proteomes; UP000032025; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 3.
DR CDD; cd18161; REC_hyHK_blue-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 2.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 3.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}.
FT DOMAIN 252..304
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 487..711
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 734..850
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 709..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 433..471
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 784
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 862 AA; 93692 MW; 32936A8215E2B300 CRC64;
MASPTSFDFL HGLSGQVVDE IVALDWQATP LGAPESWPIA LRSQLATMLA CPVPMYMVWG
PELISFYNDA YRPILGYRAD AAMGTPFRIL WGSIWDEIAP LVDKALSGQV AKVTDMRLDL
ARSGQPEESY WTFSYSPVFD DAGGIAGMIC VTGETTDRVL AERRQRASDE RLDLALSSGA
HVGLWDWDVL NDSVRSDARF AAMYGVDPAV AEGGMPIADF FRGIHPDDRD RVNNEIQAAM
AEVVAGGSPH RFVSEYRLVQ ADGTVHWVSA QGRCIPDETG RCVRFPGVSF DITERVRIEQ
QLRESEARAR LNAQRVQVAL EAGAIIGTWF WDLPSDRFTV DEPFARNFGL DPALGHEGLS
LAQVVETVHP DDRAALAEAI DAAIASGGAY AHQYRVRRHD GCYHWLEANG RVEHAPDGTP
LYFPGVLIDV GVRRALEAER DSAIAELRAL TDQLEQRVAD RTAELMRAEE ALRQSQKMEA
VGQLTGGLAH DFNNLLAGIS GSLELMALRL AQGRAGEIDR YMDAAQGATR RAAALTHRLL
AFSRRQTLAP RPTDIAALVA GMADLIRRTV GPGITVETPS PDDWWTVLVD APQLENALLN
LCINARDAMP DGGRIAIAIR NRSSRDPDDT HRDIPDGDYL MLSVTDTGTG MTPEVIEKAF
DPFFTTKPLG QGTGLGLSMI YGFARQSGGQ VRIASTVGEG TTVSLYLPRH DGPAEQDMPS
RSSAPDGARA TGETVLVVDD ESTVRLMVVD VLRDMGLQVI EAVDSASGLA LLRSDRRIDL
LITDVGLPGG MNGRQLAEAA REIRHELNVM FVTGYAESAV LNSGHLAPGM QLLTKPFTVD
ALVTGVQAAM GHQRGRYDPP AR
//
