ID A0A0C9YLI2_9AGAR Unreviewed; 1009 AA.
AC A0A0C9YLI2;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=CNH-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=K443DRAFT_127890 {ECO:0000313|EMBL:KIK08903.1};
OS Laccaria amethystina LaAM-08-1.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hydnangiaceae; Laccaria.
OX NCBI_TaxID=1095629 {ECO:0000313|EMBL:KIK08903.1, ECO:0000313|Proteomes:UP000054477};
RN [1] {ECO:0000313|EMBL:KIK08903.1, ECO:0000313|Proteomes:UP000054477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LaAM-08-1 {ECO:0000313|EMBL:KIK08903.1,
RC ECO:0000313|Proteomes:UP000054477};
RG DOE Joint Genome Institute;
RA Kuo A., Kohler A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Sun H., Tunlid A., Henrissat B.,
RA Grigoriev I.V., Hibbett D.S., Martin F., Nordberg H.P., Cantor M.N.,
RA Hua S.X.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LaAM-08-1 {ECO:0000313|Proteomes:UP000054477};
RG DOE Joint Genome Institute;
RG Mycorrhizal Genomics Consortium;
RA Kohler A., Kuo A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Riley R., Ohm R., Sun H., Tunlid A.,
RA Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.;
RT "Evolutionary Origins and Diversification of the Mycorrhizal Mutualists.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN838540; KIK08903.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C9YLI2; -.
DR STRING; 1095629.A0A0C9YLI2; -.
DR HOGENOM; CLU_001251_2_1_1; -.
DR OrthoDB; 5100844at2759; -.
DR Proteomes; UP000054477; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd04435; DEP_fRom2; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001180; CNH_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041675; PH_5.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46572; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46572:SF2; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR Pfam; PF00780; CNH; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF15405; PH_5; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00036; CNH; 1.
DR SMART; SM00049; DEP; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50219; CNH; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054477}.
FT DOMAIN 257..444
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 629..924
FT /note="CNH"
FT /evidence="ECO:0000259|PROSITE:PS50219"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1009 AA; 114944 MW; 1CB47396E97D8FA1 CRC64;
MSAAGSIKMT HDQRRSSKPP IPPSFHEGRN SPASVRPSKK TPIVYPALLS RVAEAFRERI
PLTDRVKDGL TYKDTFDGRE AVDKIAYIIK TADRNLALLL GRALDAQKFF HDVTYDHRLR
DNANELYQFR TILPSPFVSG ELASPPPDLA AIQKGLPPLP SGVFTLLTDC YSPTCSRDQL
CYSIACPRRL EQQARLNMKP QPGLSKQISR ESLGDVPVRF STFAFFPSLI IFQDDGTLWI
HSVPQEILNS VSDAEKRRQE AINEVIYTER DFVRDLEYLR DVWMNALKES DIILQSARQE
FITTVFWNIE HIIAVNTRLR DALNKRQKSF SVVEKIGDIF LDAVPHFSPF VSYGGHQLAG
KDRFEKEKSS NPAFAAFVES TERLPESRRL ELNAYLTKPI TRLARYPLLL EAVLKHTPDD
SPDKHALPQV VKMVREFLTK VNTESGKAEN RASLQKLNDA LFFKPGEDVD LRLLEEGREM
VHKGVLSKRD GELQVFLLDH AMLFTKLAKG KQQEQYKVYR RPIPLELLLI TAAEEATASI
RNQQRKNQGL VGGMPNVVSA VTTRHEAKGQ HWINFVYLGR KCYNLMLWAD SALSQRKWLE
SIFKQQQAMR ERSMIFDTVT LSEGFFSGPN KVNCAAPFDR GRSIVYGTDD GVYISSFTSP
ENEPVKVLAL LDVLQVDVLE EYELLIVLSE RQVITFPLEA LDKRDPMAGL RRAKRISSHT
SFFKAGFCLG RVLVCIVKSS QLSSTFKTLE PIDQNIRGRA KPTFRKLLQG GNDTLKMFRE
FYIPVESTSI HYLKTKMCVG CSKGFEIVDL ETLDTQGLLD PHDESLDFVR RRDNLRPMAI
YRIHNEFLLC YDEFAFYVNK NGRRSRLNFM VQWEGQPTGF ALHEPYVLAF EPSFVEIRHI
ETGLLSQVIQ GFNLRLLFAD TPPSVTNTAT QQYNPHQGYH QNLTTTFRPY GNYGHLTQQA
PYISQPRHIQ GVGRDEILIV SEDRVLALRT AAGPQRFMSD DGSMMSMPR
//
