ID A0A0D0HXS8_9MICO Unreviewed; 658 AA.
AC A0A0D0HXS8;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=SD72_09230 {ECO:0000313|EMBL:KIP52401.1};
OS Leucobacter komagatae.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Leucobacter.
OX NCBI_TaxID=55969 {ECO:0000313|EMBL:KIP52401.1, ECO:0000313|Proteomes:UP000032120};
RN [1] {ECO:0000313|EMBL:KIP52401.1, ECO:0000313|Proteomes:UP000032120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM ST2845 {ECO:0000313|EMBL:KIP52401.1,
RC ECO:0000313|Proteomes:UP000032120};
RA Karlyshev A.V., Kudryashova E.B.;
RT "Draft genome sequence of Leucobacter komagatae strain VKM ST2845.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIP52401.1}.
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DR EMBL; JXSQ01000011; KIP52401.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D0HXS8; -.
DR Proteomes; UP000032120; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd06577; PASTA_pknB; 4.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.30.10.20; -; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR030616; Aur-like.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR NCBIfam; NF033483; PknB_PASTA_kin; 1.
DR PANTHER; PTHR24350:SF30; AURORA KINASE; 1.
DR PANTHER; PTHR24350; SERINE/THREONINE-PROTEIN KINASE IAL-RELATED; 1.
DR Pfam; PF03793; PASTA; 2.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00740; PASTA; 4.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51178; PASTA; 2.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000032120};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 18..282
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 388..453
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 591..655
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT REGION 328..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 658 AA; 69791 MW; CB739B3280D85AD2 CRC64;
MTAPPIDPLI GQTLDARYVI RSRIARGGMA MVYLAHDLRL ERRVAVKVMH EHLAEDENFT
RRFDREARSA ARLSHTNLVN VFDQGKDLGR VYLVMEYLPS ITLRELLKKQ QRLTLDQSLE
IGDAILAGLA AAHSAGIVHR DLKPENVLLV DDGRIKIGDF GLARAVSANT TTGQALLGTI
AYLSPELVTR GIADERSDLY AFGIMLYEML TGAQPFTGEQ PMQIAYQHAH SDVPPPSDAA
DVSTPAIDHF VVWLTQRNPE LRPANAGEAL VHMRELRQDP YRVSEALATA VIPAGAVPGE
TTVLPASALP DDAATTHLTP STTVLNRAEQ STLQSTGSET PQQPGSDADR AREQGARRSR
NGRITAGVVT LLLAATAGVA LWFGQGPGSA VTVPDVSGTP MEEAQLSLEE LDLVVNTGEC
ASLDVAVGLA AGVDPEPGTR LDRGSEVTLC QSTGPELLAV PTLVGLSLDD AIARIEESRF
TFGEVTDTRF SDAPADEVLA ALDADEAELG DTFPERSTIN LVVSAGPAPG VSGMSVEQAT
QTLADRQLTV DSASNTEVIS DDVPRGKVVG VVWLTDPVRP GDSVGLQISS GPELFEIPDI
AGLGLQEAMD TLESAGFSPT TLVPEALRSL AKATGTNPAA GERVEAGTEI RVTSQLSL
//
