ID A0A0D0X681_9ACTN Unreviewed; 840 AA.
AC A0A0D0X681;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Metallophosphoesterase {ECO:0000313|EMBL:KIR66656.1};
GN ORFNames=TK50_02295 {ECO:0000313|EMBL:KIR66656.1};
OS Micromonospora haikouensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=686309 {ECO:0000313|EMBL:KIR66656.1, ECO:0000313|Proteomes:UP000032254};
RN [1] {ECO:0000313|EMBL:KIR66656.1, ECO:0000313|Proteomes:UP000032254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JXNU-1 {ECO:0000313|EMBL:KIR66656.1,
RC ECO:0000313|Proteomes:UP000032254};
RA Long Z., Huang Y., Jiang Y.;
RT "Sequencing and annotation of Micromonospora carbonacea strain JXNU-1
RT genome.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIR66656.1}.
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DR EMBL; JXSX01000001; KIR66656.1; -; Genomic_DNA.
DR RefSeq; WP_043963687.1; NZ_JXSX01000001.1.
DR AlphaFoldDB; A0A0D0X681; -.
DR PATRIC; fig|47853.6.peg.496; -.
DR OrthoDB; 9807890at2; -.
DR Proteomes; UP000032254; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd07423; MPP_Prp_like; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041780; MPP_PrpE-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR024028; PNKP_bac.
DR InterPro; IPR032380; PNKP_ligase_dom.
DR NCBIfam; TIGR04075; bacter_Pnkp; 1.
DR PANTHER; PTHR42850:SF7; BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE PRPE [ASYMMETRICAL]; 1.
DR PANTHER; PTHR42850; METALLOPHOSPHOESTERASE; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF16542; PNKP_ligase; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000032254}.
FT DOMAIN 180..375
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 462..835
FT /note="Polynucleotide kinase-phosphatase ligase"
FT /evidence="ECO:0000259|Pfam:PF16542"
SQ SEQUENCE 840 AA; 90608 MW; 5497556FFC3629E1 CRC64;
MIEIPELALV ALVGVSGSGK STFARRHFAP SQVLSSDAFR GMVADDENDQ SASADAFDAL
HHVAGIRLRR GLLTVVDATN LQPHARAGLV RVAREHDVLP VAIVLDVPEA VAWERTQGRA
DRTHGRQVLT RMQRDLRQSY GRLAREGFRK VHVLRGVDEI DAAQIRYEKL FNDRRELTGP
FDIVGDVHGC REELEALLLR LGYVLRRDDA GRPVDAVHPA GRTPVFVGDL VDRGPDSPGV
LRLVMGMVAA GHAICVPGNH EQKLLRRLRG RDVRLTHGLA ETMAQLDAED PAFVAEVATF
VDGLVSHFVL DGGRLVVAHA GLKEEYHGRA SGRVRSFALY GETTGETDEY GLPVRYPWAR
DYRGSAMVVY GHTPTPEPEW VNNTICVDTG CVFGGKLTAL RYPEKELVSV PAVKEWYAPA
RPLVAPAPAR PDAVLDLRDV TGRRHVEHAY GTLTVPAENA AAALEVMSRF AVDPRWLTWL
PPTMAPCSTA TADGFLEHPA QAFADYRAAG VDRVVCEEKH MGSRAVVLVC RDPDGGPFGP
GGGVVHTRTG RPFFGPPLDG ELLGRVRAAV GVAGLWAELD TDWLLLDCEL LPWSAKAGGL
IREQYASVGA AGRAALPAVL ATLDAAAGRG LPVGDLRARM AARRADVEAY SAAYRAYVAP
TDGLAGVTLA PFAVLASAGA SHVERDHGWH LDLADRLCAA DPGFFTVTRR RVVDLADASA
EADATGWWLA LTAAGGEGMV VKPYAGLASR SPKGSLLQPG IKCRGREYLR IIYGPGYTEP
EQLAALRRRS LGRKRGLALR EHALGLAALA ALADGAPLWR RHELVFAVLA CESEPVDPRL
//
