ID A0A0D1CL33_9RHOB Unreviewed; 295 AA.
AC A0A0D1CL33;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=GarR_2 protein {ECO:0000313|EMBL:KIT15507.1};
DE EC=1.1.1.60 {ECO:0000313|EMBL:KIT15507.1};
GN Name=garR_2 {ECO:0000313|EMBL:KIT15507.1};
GN ORFNames=jaqu_27550 {ECO:0000313|EMBL:KIT15507.1};
OS Jannaschia aquimarina.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Jannaschia.
OX NCBI_TaxID=935700 {ECO:0000313|EMBL:KIT15507.1, ECO:0000313|Proteomes:UP000032232};
RN [1] {ECO:0000313|EMBL:KIT15507.1, ECO:0000313|Proteomes:UP000032232}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GSW-M26 {ECO:0000313|EMBL:KIT15507.1,
RC ECO:0000313|Proteomes:UP000032232};
RA Voget S., Daniel R.;
RT "Genome Sequence of Jannaschia aquimarina DSM28248, a member of the
RT Roseobacter clade.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIT15507.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYFE01000049; KIT15507.1; -; Genomic_DNA.
DR RefSeq; WP_043919547.1; NZ_JYFE01000049.1.
DR AlphaFoldDB; A0A0D1CL33; -.
DR STRING; 935700.jaqu_27550; -.
DR PATRIC; fig|935700.4.peg.2853; -.
DR OrthoDB; 9812907at2; -.
DR Proteomes; UP000032232; Unassembled WGS sequence.
DR GO; GO:0008679; F:2-hydroxy-3-oxopropionate reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43060:SF15; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000313|EMBL:KIT15507.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000032232}.
FT DOMAIN 3..160
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 164..276
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 170
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 295 AA; 30726 MW; C68F61AFF78D8CDE CRC64;
MERIGFVGVG LMGEGMAASM LKAGYPVTVI AHMNRAPVER LLELGAREAQ TLEDLAANAD
VLHICAPGSP QVETIVEKVL PELPKGSVVI DCSTSDPVST VMLAKRIEAA GSHMADAPLG
GTPAQAAEGQ LAAMVGADET TFARIEPILR SWAGAAVAHL GPVGTGHRMK LLNNFLAMGY
GALYAEALAL SRKVGISTET FDGVIRGSRM DCGFYQTFMG YAVEGNRDSH KFTLTNALKD
MTYLASMAGA AGIANPVGAA IRNSYAGAVS QGGDGSEDYV PHLVDFVARA NGLDE
//
