ID   A0A0D1LI88_9MYCO        Unreviewed;       767 AA.
AC   A0A0D1LI88;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Formate dehydrogenase {ECO:0000313|EMBL:KIU18182.1};
GN   ORFNames=TL10_03795 {ECO:0000313|EMBL:KIU18182.1};
OS   Mycolicibacterium llatzerense.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=280871 {ECO:0000313|EMBL:KIU18182.1, ECO:0000313|Proteomes:UP000032221};
RN   [1] {ECO:0000313|EMBL:KIU18182.1, ECO:0000313|Proteomes:UP000032221}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLUC14 {ECO:0000313|EMBL:KIU18182.1,
RC   ECO:0000313|Proteomes:UP000032221};
RA   Greninger A.L., Langelier C., Cunningham G., Chiu C.Y., Miller S.;
RT   "Genome sequence of Mycobacterium llatzerense and Mycobacterium immunogenum
RT   recovered from brain abscess.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mo-bis(molybdopterin guanine dinucleotide);
CC         Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KIU18182.1}.
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DR   EMBL; JXST01000004; KIU18182.1; -; Genomic_DNA.
DR   RefSeq; WP_043984568.1; NZ_LXOV01000001.1.
DR   AlphaFoldDB; A0A0D1LI88; -.
DR   STRING; 280871.TL10_03795; -.
DR   PATRIC; fig|280871.6.peg.771; -.
DR   OrthoDB; 5287431at2; -.
DR   Proteomes; UP000032221; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR   CDD; cd02787; MopB_CT_ydeP; 1.
DR   CDD; cd02767; MopB_ydeP; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR037951; MopB_CT_YdeP.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR010046; Mopterin_OxRdtse_a_bac.
DR   InterPro; IPR041953; YdeP_MopB.
DR   NCBIfam; TIGR01701; Fdhalpha-like; 1.
DR   PANTHER; PTHR43105:SF4; PROTEIN YDEP; 1.
DR   PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   PIRSF; PIRSF000144; CbbBc; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032221}.
FT   DOMAIN          124..500
FT                   /note="Molybdopterin oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00384"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..22
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   767 AA;  84819 MW;  4D9C05E3F7E5529C CRC64;
     MTDRSTEQRT ESDEHGEPEF KPYHHPAAGW GAAISVTKFL AREREPISGP HAIMKMNHED
     GGFDCPGCAW PDDMKGLKLD ICENGIKHVT WEMTHKRCGP EFFAQHTVSE LAEWSDFALE
     DTGRLTEPMV YDAATDRYKP ISWRDAFDLV GRALADLDDP NQASYYTSGR LGNEATFLYQ
     LLARELGTNN LPDCSNMCHE ASGRAMQASL GTGKGTVDLE DWEAADALFV IGVNAASNAP
     RMLTALSEAY RRGAQIVHIN PLVEAGATKT IIPHDFLRMA TFKSTKTSTL NLQPRIGGDM
     ALIRGIAKVV LEQSETDPKA LDIEFIERYT SGFEAYRAAV EATSWDEIVY KSGVSERDIR
     RAAKIYRDAD RSIISWCLGV TQHEHGVDSV REIVNLLLLR GNLGREGAGP SPVRGHSNVQ
     GNRTCGIDHR PAEAFLERLG EVCGIDPPRA HGLDTVHTIE GMHTGDVKVF IGMGGNFASA
     APDTAYTFEG LQKCDLTVQV STKLNRSHVI HGRQALILPC LGRTEKDHQK EGIQSTSVED
     SMSMVHLSVG MKKPASPHLL SEPAIIAGIA AAALPQSQTP WHWYVEDYDR IRDTMAKVLN
     GFEDFNRRVR LPLGFRIKQP ARELIFLTPS GRAEFSAVEL PDDTVSEGTL ILATLRSHDQ
     WNTTVYSDND RYRGIKNLRT LIFMNERDMG DRGIKEFDDV DIVATARDGS VRSLRRYKAV
     PYGIPRGNAA GYMPEMNVLC AIGDFSTQSD QPIMKNVKVT VTKSAGD
//